Babenkov H D, Dolhopolov V V, Potiĭ V V, Shypilov K V, Peleshenko O S
Klin Khir. 2006 Jul(7):58-60.
The influence of photochemically activated 40% solution of Levomecol ointment toward the tissue apoptosis while occurrence of ischemic complications of diabetes mellitus was studied in experiment on 184 adult mongrel white male rats weighted 250-310 g. While modelling of ischemic complications of diabetes mellitus there was revealed the cells apoptosis regulation in soft tissues of the affected lower extremities, causing worsening of the reparative processes course. Application of photochemically activated 40% solution of Levomecol ointment had promoted an effective correction of disorders in the cells apoptosis regulation. It substantiates the expediency of the method introduction into clinical practice.
在184只体重250 - 310克的成年雄性杂种白色大鼠身上进行实验,研究光化学激活的40%利沃莫尔软膏溶液对糖尿病缺血性并发症发生时组织凋亡的影响。在模拟糖尿病缺血性并发症时,发现受影响下肢软组织中的细胞凋亡调节出现异常,导致修复过程恶化。应用光化学激活的40%利沃莫尔软膏溶液促进了细胞凋亡调节紊乱的有效纠正。这证实了将该方法引入临床实践的合理性。