Villani Flavio, D'Amico Domenico, Pincherle Alessandro, Tullo Vincenzo, Chiapparini Luisa, Bussone Gennaro
Division of Clinical Epileptology, Instituto Nazionale Neurologico "C. Besta", Milan, Italy.
Epilepsia. 2006 Nov;47(11):1949-52. doi: 10.1111/j.1528-1167.2006.00804.x.
Focal negative motor (akinetic) seizures are rare ictal events that are diagnostically challenging because they are difficult to differentiate from postictal Todd paresis, transient ischemic attacks, migraine events, and psychogenic episodes.
We describe a 45-year-old man in whom, after surgical drainage of a right frontoparietal subdural hematoma, prolonged episodes developed with flaccid paralysis of the left arm.
A video-EEG recording demonstrated a close relation between the focal motor impairment and a clear-cut epileptic ictal discharge involving the right perirolandic cortical areas.
On the basis of the electroclinical data, we hypothesize the involvement of the primary motor area in the genesis of the epileptic discharge triggering focal negative seizures.
局灶性负性运动性(运动不能性)癫痫发作是罕见的发作期事件,因其难以与发作后托德麻痹、短暂性脑缺血发作、偏头痛事件及心因性发作相鉴别,故诊断具有挑战性。
我们描述了一名45岁男性,在其右侧额顶叶硬膜下血肿进行手术引流后,出现了左臂弛缓性麻痹的持续性发作。
视频脑电图记录显示局灶性运动障碍与累及右侧中央旁小叶皮质区域的明确癫痫发作期放电之间存在密切关系。
基于电临床数据,我们推测原发性运动区参与了触发局灶性负性癫痫发作的癫痫放电的发生过程。