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浮动电极介电泳

Floating electrode dielectrophoresis.

作者信息

Golan Saar, Elata David, Orenstein Meir, Dinnar Uri

机构信息

Department of Bio-Medical Engineering, Technion, Israel Institute of Technology, Haifa, Israel.

出版信息

Electrophoresis. 2006 Dec;27(24):4919-26. doi: 10.1002/elps.200600208.

Abstract

In practice, dielectrophoresis (DEP) devices are based on micropatterned electrodes. When subjected to applied voltages, the electrodes generate nonuniform electric fields that are necessary for the DEP manipulation of particles. In this study, electrically floating electrodes are used in DEP devices. It is demonstrated that effective DEP forces can be achieved by using floating electrodes. Additionally, DEP forces generated by floating electrodes are different from DEP forces generated by excited electrodes. The floating electrodes' capabilities are explained theoretically by calculating the electric field gradients and demonstrated experimentally by using test-devices. The test-devices show that floating electrodes can be used to collect erythrocytes (red blood cells). DEP devices which contain many floating electrodes ought to have fewer connections to external signal sources. Therefore, the use of floating electrodes may considerably facilitate the fabrication and operation of DEP devices. It can also reduce device dimensions. However, the key point is that DEP devices can integrate excited electrodes fabricated by microtechnology processes and floating electrodes fabricated by nanotechnology processes. Such integration is expected to promote the use of DEP devices in the manipulation of nanoparticles.

摘要

在实际应用中,介电泳(DEP)装置基于微图案化电极。当施加电压时,电极会产生非均匀电场,这对于DEP操纵颗粒是必需的。在本研究中,DEP装置中使用了电浮置电极。结果表明,使用浮置电极可以实现有效的DEP力。此外,浮置电极产生的DEP力与激励电极产生的DEP力不同。通过计算电场梯度从理论上解释了浮置电极的性能,并通过使用测试装置进行了实验验证。测试装置表明,浮置电极可用于收集红细胞。包含许多浮置电极的DEP装置与外部信号源的连接应该更少。因此,使用浮置电极可能会极大地促进DEP装置的制造和操作。它还可以减小装置尺寸。然而,关键在于DEP装置可以集成通过微技术工艺制造的激励电极和通过纳米技术工艺制造的浮置电极。这种集成有望促进DEP装置在纳米颗粒操纵中的应用。

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