Zinin Alexander I, Malysheva Nelly N, Shpirt Anna M, Torgov Vladimir I, Kononov Leonid O
N. D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences, Leninsky prosp., 47, 119991 Moscow, Russian Federation.
Carbohydr Res. 2007 Feb 26;342(3-4):627-30. doi: 10.1016/j.carres.2006.10.009. Epub 2006 Oct 13.
Methanesulfonic acid was shown to be an efficient and convenient substitute for ethereal HCl in reductive 4,6-O-benzylidene acetal ring-opening reaction with sodium cyanoborohydride in THF. Normal regioselectivity was observed, the 6-O-benzyl ethers with free 4-OH group being the major products of the reaction.
在四氢呋喃（THF）中，用氰基硼氢化钠进行还原4,6-O-亚苄基缩醛开环反应时，甲磺酸被证明是一种有效且方便的盐酸醚替代物。观察到正常的区域选择性，带有游离4-OH基团的6-O-苄基醚是该反应的主要产物。
