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尽管接受治疗仍患有高血压:瑞典南部一项基于初级医疗保健的横断面研究结果

High blood pressure despite treatment: results from a cross-sectional primary healthcare-based study in southern Sweden.

作者信息

Hedblad Bo, Nerbrand Christina, Ekesbo Richard, Johansson Lennart, Midlöv Patrik, Brunkstedt Inger, Svensson Per, Gyllerup Staffan, Sträng Birgitta, Persson Robert, Janzon Lars

机构信息

Department of Clinical Sciences in Malmö, Epidemiological Research Group, Sweden.

出版信息

Scand J Prim Health Care. 2006 Dec;24(4):224-30. doi: 10.1080/02813430601002134.

Abstract

OBJECTIVE

To study degree of blood pressure (BP) control in primary healthcare (PHC) treated hypertensive patients in relation to sex, age, drug treatment, and concomitant diseases.

DESIGN

Random sample of patients with hypertension.

SETTING

Ten PHC centres in the Region of Skåne, Sweden.

SUBJECTS

All the 30- to 95-year-old patients with hypertension who during the period 12 September to 24 September 2004 attended their PHC (146 men and 229 women).

MAIN OUTCOME MEASURES

Achievement of BP control (< 140/90 mmHg) according to European guidelines.

RESULTS

Some 90% had been treated > 12 months, 40% had mono-therapy, 15% > or = 3 drugs. Use of diuretics was more common in women while use of ACE inhibitors and calcium channel blockers was common in men. Inadequate BP control was related to age; only 22% had BP < 140/90 mmHg, 38% had a BP > or = 160/100 mmHg. BP decline was inversely related to BP measured 12 months or more prior to the present follow-up (r = - 0.64, p < 0.001, for systolic and r = - 0.67, p < 0.001, for diastolic BP). The systolic or diastolic BP had in every fifth patient during treatment increased by > or = 10 mmHg. No association was found between average BP decline and prescribed number of drugs.

CONCLUSION

A minority of the patients had BP below the level (< 140/90 mmHg) recommended by European guidelines. This study illustrates the need for continued follow-up of defined groups of patients in order to improve quality of care.

摘要

目的

研究基层医疗保健(PHC)机构中接受治疗的高血压患者的血压控制程度与性别、年龄、药物治疗及伴发疾病之间的关系。

设计

高血压患者随机样本。

地点

瑞典斯科讷地区的10个基层医疗保健中心。

研究对象

2004年9月12日至9月24日期间前往其基层医疗保健机构就诊的所有30至95岁高血压患者(146名男性和229名女性)。

主要观察指标

根据欧洲指南实现血压控制(<140/90 mmHg)。

结果

约90%的患者接受治疗超过12个月,40%采用单一疗法,15%使用≥3种药物。利尿剂在女性中使用更为普遍,而血管紧张素转换酶抑制剂和钙通道阻滞剂在男性中使用较为常见。血压控制不佳与年龄有关;只有22%的患者血压<140/90 mmHg,38%的患者血压≥160/100 mmHg。血压下降与本次随访前12个月或更长时间测量的血压呈负相关(收缩压r = -0.64,p < 0.001;舒张压r = -0.67,p < 0.001)。治疗期间每五名患者中就有一名患者的收缩压或舒张压升高≥10 mmHg。未发现平均血压下降与所开药物数量之间存在关联。

结论

少数患者的血压低于欧洲指南推荐的水平(<140/90 mmHg)。本研究表明,需要对特定患者群体持续进行随访,以提高医疗质量。

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