Falcini F, Taccetti G, Trapani S, Tafi L, Volpi M
Department of Paediatrics, University of Florence, Italy.
Clin Exp Rheumatol. 1991 Jan-Feb;9 Suppl 6:37-40.
Steroids are widely used for treating chronic connective tissue diseases in both adults and children. Unfortunately steroid treatment may produce many side effects and growth retardation is one of these. In juvenile chronic arthritis patients (JCA) oral steroids are mainly administered in severe systemic or polyarticular onset or in JCA complicated by chronic uveitis which is unresponsive to mydriatic and steroid eye drops. Intraarticular steroid treatment is used in pauciarticular onset JCA. This paper will review the literature on steroid treatment and growth rate, and report 35 cases of children with JCA treated with steroids.
类固醇广泛用于治疗成人和儿童的慢性结缔组织疾病。不幸的是，类固醇治疗可能会产生许多副作用，生长发育迟缓就是其中之一。在幼年慢性关节炎患者（JCA）中，口服类固醇主要用于严重的全身型或多关节型发病，或用于并发对散瞳剂和类固醇眼药水无反应的慢性葡萄膜炎的JCA患者。关节内类固醇治疗用于少关节型发病的JCA患者。本文将综述有关类固醇治疗与生长速率的文献，并报告35例接受类固醇治疗的JCA儿童病例。
