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[患有肝脾曼氏血吸虫病患者的淋巴瘤]

[Lymphoma in patients harboring hepatosplenic mansonic schistosomiasis].

作者信息

Ferraz Alvaro Antônio Bandeira, de Sá Vladimir Curvêlo Tavares, Lopes Edmundo Pessoa de Almeida, de Araújo José Guido Corrêa, Martins Antônio Cavalcanti de Albuquerque, Ferraz Edmundo Machado

机构信息

Departamento de Cirurgia, Universidade Federal de Pernambuco, Recife, PE.

出版信息

Arq Gastroenterol. 2006 Apr-Jun;43(2):85-8. doi: 10.1590/s0004-28032006000200005.

DOI:10.1590/s0004-28032006000200005
PMID:17119660
Abstract

BACKGROUND

Correlation between infectious agents and linfoproliferative diseases are more stablished, over all virus and bacteria, through the activation of linfocytes.

AIM

To describe six new cases, of a series of 254 patients (2,36%) with mansonic schistosomiasis, in the hepatosplenic form.

METHODS

Six patients will be described, amongst the 254 carriers of mansonic schistosomiasis, in the hepatosplenic form, followed in the last 13 years.

RESULTS

All the six cases had occurred in women. The histopathologic examinations had evidenced two cases of marginal splenic zone lymphomas, one of great cells with immunoblasts lymphomas, one diffuse lymphomas, a great cells malignant lymphomas, a great not clivads cells, and another case of Hodgkin. Half of the six evolved for the death 4-15 months after the diagnosis. The others three persist in accompaniment in the Oncology Division of the Clinics Hospital.

CONCLUSION

The incidence of lymphomas in the 254 mansonic schistosomiasis patients followed in our clinic was of 2,36%. At last, this article intends to call the attention, for the occurrence of lymphomas, in the spleen of patients with mansonic schistosomiasis, in the hepatosplenic form.

摘要

背景

通过淋巴细胞的激活,感染因子与淋巴增殖性疾病之间的相关性在所有病毒和细菌中得到了更充分的确立。

目的

描述254例曼氏血吸虫病肝脾型患者(占2.36%)中的6例新病例。

方法

将描述在过去13年中随访的254例曼氏血吸虫病肝脾型携带者中的6例患者。

结果

所有6例均发生在女性。组织病理学检查证实2例为脾边缘区淋巴瘤,1例为免疫母细胞大细胞淋巴瘤,1例为弥漫性淋巴瘤,1例为大细胞恶性淋巴瘤,1例为大的非克利夫斯细胞淋巴瘤,另1例为霍奇金淋巴瘤。6例中有一半在诊断后4至15个月死亡。另外3例仍在临床医院肿瘤科接受随访。

结论

在我们诊所随访的254例曼氏血吸虫病患者中,淋巴瘤的发病率为2.36%。最后,本文旨在引起人们对曼氏血吸虫病肝脾型患者脾脏中淋巴瘤发生情况的关注。

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[Lymphoma in patients harboring hepatosplenic mansonic schistosomiasis].[患有肝脾曼氏血吸虫病患者的淋巴瘤]
Arq Gastroenterol. 2006 Apr-Jun;43(2):85-8. doi: 10.1590/s0004-28032006000200005.
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Follicular lymphoma of the spleen in patients with hepatosplenic Schistosomiasis mansoni.曼氏血吸虫病所致肝脾肿大患者的脾脏滤泡性淋巴瘤
Am J Trop Med Hyg. 1971 Mar;20(2):237-43. doi: 10.4269/ajtmh.1971.20.237.
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[Patient with chronic Chagas heart disease, hepatosplenic schistosomiasis and acquired immunodeficency syndrome: possible spontaneous resolution of thrombus in the right ventricle].[患有慢性恰加斯心脏病、肝脾血吸虫病和获得性免疫缺陷综合征的患者:右心室血栓可能自发溶解]
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[Evaluation of the permeability of distal splenorenal anastomosis, by ultrasonography and angiography in hepatosplenic form of schistosomiasis mansoni].[通过超声检查和血管造影术评估曼氏血吸虫病肝脾型远端脾肾吻合术的通透性]
Rev Hosp Clin Fac Med Sao Paulo. 1986 Nov-Dec;41(6):260-6.
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Clinical staging of malignant lymphoma in patients suspected to have hepato-splenic schistosomiasis.疑似肝脾血吸虫病患者恶性淋巴瘤的临床分期
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Increased Hepatic Arterial Blood Flow Measured by Hepatic Perfusion Index in Hepatosplenic Schistosomiasis: New Concepts for an Old Disease.通过肝灌注指数测量肝脾型血吸虫病患者肝动脉血流增加:一种古老疾病的新概念
Dig Dis Sci. 2016 Jul;61(7):2118-26. doi: 10.1007/s10620-016-4080-y. Epub 2016 Feb 26.

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