Ferraz Alvaro Antônio Bandeira, de Sá Vladimir Curvêlo Tavares, Lopes Edmundo Pessoa de Almeida, de Araújo José Guido Corrêa, Martins Antônio Cavalcanti de Albuquerque, Ferraz Edmundo Machado
Departamento de Cirurgia, Universidade Federal de Pernambuco, Recife, PE.
Arq Gastroenterol. 2006 Apr-Jun;43(2):85-8. doi: 10.1590/s0004-28032006000200005.
Correlation between infectious agents and linfoproliferative diseases are more stablished, over all virus and bacteria, through the activation of linfocytes.
To describe six new cases, of a series of 254 patients (2,36%) with mansonic schistosomiasis, in the hepatosplenic form.
Six patients will be described, amongst the 254 carriers of mansonic schistosomiasis, in the hepatosplenic form, followed in the last 13 years.
All the six cases had occurred in women. The histopathologic examinations had evidenced two cases of marginal splenic zone lymphomas, one of great cells with immunoblasts lymphomas, one diffuse lymphomas, a great cells malignant lymphomas, a great not clivads cells, and another case of Hodgkin. Half of the six evolved for the death 4-15 months after the diagnosis. The others three persist in accompaniment in the Oncology Division of the Clinics Hospital.
The incidence of lymphomas in the 254 mansonic schistosomiasis patients followed in our clinic was of 2,36%. At last, this article intends to call the attention, for the occurrence of lymphomas, in the spleen of patients with mansonic schistosomiasis, in the hepatosplenic form.
通过淋巴细胞的激活,感染因子与淋巴增殖性疾病之间的相关性在所有病毒和细菌中得到了更充分的确立。
描述254例曼氏血吸虫病肝脾型患者(占2.36%)中的6例新病例。
将描述在过去13年中随访的254例曼氏血吸虫病肝脾型携带者中的6例患者。
所有6例均发生在女性。组织病理学检查证实2例为脾边缘区淋巴瘤,1例为免疫母细胞大细胞淋巴瘤,1例为弥漫性淋巴瘤,1例为大细胞恶性淋巴瘤,1例为大的非克利夫斯细胞淋巴瘤,另1例为霍奇金淋巴瘤。6例中有一半在诊断后4至15个月死亡。另外3例仍在临床医院肿瘤科接受随访。
在我们诊所随访的254例曼氏血吸虫病患者中,淋巴瘤的发病率为2.36%。最后,本文旨在引起人们对曼氏血吸虫病肝脾型患者脾脏中淋巴瘤发生情况的关注。