[一氧化氮合酶在食蟹猴睾丸和附睾中的表达及作用]
[Expression and role of nitric oxide synthase in the testis and epididymis of Macaca fascicularis].
作者信息
Sun Li, Ren Ya-Ping, Jiang Wei, Zhang Mei-Yan, Hou Qiao-Yan
机构信息
Department of Histology and Embryology, Guilin Medical College, Guilin, Guangxi 541004, China.
出版信息
Zhonghua Nan Ke Xue. 2006 Oct;12(10):876-8.
OBJECTIVE
To investigate the expression and the role of nitric oxide synthase (NOS) in the testis and epididymis of macaca fascicularis.
METHODS
The immunohistochemical ABC method was used to observe the localization of nitric oxide synthase in the testis and epididymis of the macaca fascicularis.
RESULTS
(1) nNOS immunoreactivity was found in the spermatogenic cells of seminiferous tubules, the epithelia of epididymal efferent ducts, sperm and the endothelia of blood vessels; (2) iNOS was expressed in the epididymal efferent duct, the sperm inside the duct, and the myoid cells and endothelia of blood vessels; (3) eNOS immunoreactivity was detected in the interstitial cells of the testis, the epididymal efferent duct, the sperm inside the duct, and the myoid cells and endothelia of blood vessels.
CONCLUSION
NOS is extensively expressed in the testis and epididymis of the macaca fascicularis and it may play an important role in such processes as spermatogenesis, sperm maturation and testosterone secretion.
目的
研究一氧化氮合酶（NOS）在食蟹猴睾丸和附睾中的表达及作用。
方法
采用免疫组织化学ABC法观察一氧化氮合酶在食蟹猴睾丸和附睾中的定位。
结果
（1）在生精小管的生精细胞、附睾输出小管上皮、精子及血管内皮中发现nNOS免疫反应性；（2）iNOS在附睾输出小管、管内精子以及血管的肌样细胞和内皮中表达；（3）在睾丸间质细胞、附睾输出小管、管内精子以及血管的肌样细胞和内皮中检测到eNOS免疫反应性。
结论
NOS在食蟹猴睾丸和附睾中广泛表达，可能在精子发生、精子成熟和睾酮分泌等过程中发挥重要作用。
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