撒哈拉以南非洲农村地区一家医院预防手术部位感染的抗菌药物预防措施
Antimicrobial prophylaxis to prevent surgical site infections in a rural sub-Saharan hospital.
作者信息
Fehr J, Hatz C, Soka I, Kibatala P, Urassa H, Battegay M, Jeffrey Z, Smith T, Mshinda H, Frei R, Widmer A F
机构信息
Department of Medicine and Diagnostics, Swiss Tropical Institute, Basel, Switzerland.
出版信息
Clin Microbiol Infect. 2006 Dec;12(12):1224-7. doi: 10.1111/j.1469-0691.2006.01551.x.
A prospective cohort study was performed to collect baseline data concerning surgical site infections (SSIs) and antimicrobial prophylaxis (AMP) in a remote sub-Saharan district hospital. The SSI rate of 22% was high. Most (88%) of the patients received prophylaxis after incision, and only 5% within the 30-min period before incision. Of all pathogens isolated from SSIs, 60% were resistant to the agent administered. The antibiotics given most frequently were chloramphenicol (60%), aminopenicillins (23%) and benzylpenicillin (15%). Staphylococcus aureus (36%), Escherichia coli (5%) and enterococci (4%) were the pathogens isolated most commonly from SSIs.
在撒哈拉以南地区的一家偏远区级医院开展了一项前瞻性队列研究，以收集有关手术部位感染（SSI）和抗菌药物预防（AMP）的基线数据。22%的手术部位感染率很高。大多数（88%）患者在切口后接受预防用药，只有5%在切口前30分钟内用药。从手术部位感染中分离出的所有病原体中，60%对所使用的药物耐药。最常使用的抗生素是氯霉素（60%）、氨基青霉素（23%）和苄青霉素（15%）。金黄色葡萄球菌（36%）、大肠杆菌（5%）和肠球菌（4%）是从手术部位感染中最常分离出的病原体。
Zotero 插件