Department of General Surgery, The Aga Khan University, Dar es Salaam, Tanzania.
Department of Nursing and Midwifery, The Aga Khan University, Dar es Salaam, Tanzania.
PLoS One. 2021 Aug 26;16(8):e0256134. doi: 10.1371/journal.pone.0256134. eCollection 2021.
Surgical Site Infections are a major cause of morbidity and mortality among operated patients. In spite of the accessibility of universal and national guidelines for surgical prophylaxis, recent studies surveying the present routine of prophylaxis have demonstrated overutilization of a wide range antibacterial medication for a single patient. Few studies have shown qualitatively factors influencing this and perceptions of surgeons on surgical antibiotic prophylaxis use. Unfortunately, none of these studies have been done in Tanzania.
To describe the perceptions of surgeons on surgical antibiotic prophylaxis use at an urban tertiary hospital.
A qualitative study involving in-depth interviews with surgeons was conducted in English by the primary investigator. The interviews were audio-recorded and transcribed verbatim. Systematic text condensation by Malterud was used for data analysis.
Fourteen surgeons and obstetrics and gynaecologists participated. Their perceptions were summarized into three main categories: Inadequate data to support practice; one who sees the patient decides the antibiotic prophylaxis; prolonged antibiotic use for fear of unknown. The participants perceived that choice of antibiotic should be based on local hospital data for bacterial resistance pattern, however the hospital guidelines and data for surgical site infection rates are unknown. Fear of getting infection and anticipating complications led to prolonged antibiotics use.
The study provides an understanding of surgical antibiotic prophylaxis use and its implementation challenges. This was partly expressed by unavailability of local data and guidelines to enhance practice. To improve this, there is a need of guidelines that incorporates local resistance surveillance data and enhanced antibiotic stewardship programmes. A strong consideration should be placed into ways to combat the fears of surgeons for complications, as these significantly affect the current practise with use of surgical antibiotic prophylaxis.
手术部位感染是手术患者发病率和死亡率的主要原因。尽管普遍存在针对手术预防的国家指南,但最近调查预防现状的研究表明,对单个患者过度使用了广泛的抗菌药物。一些研究已经定性地显示了影响这一点的因素以及外科医生对手术抗生素预防使用的看法。不幸的是,这些研究都没有在坦桑尼亚进行过。
描述城市三级医院外科医生对手术抗生素预防使用的看法。
主要调查员以英语进行了一项涉及外科医生深入访谈的定性研究。访谈进行了录音,并逐字转录。采用 Malterud 的系统文本浓缩法进行数据分析。
共有 14 名外科医生和妇产科医生参与。他们的看法总结为三个主要类别:缺乏支持实践的数据;一个看到患者的人决定抗生素预防;由于担心未知因素,抗生素使用时间延长。参与者认为抗生素的选择应基于当地医院的细菌耐药模式数据,但医院的指南和手术部位感染率的数据是未知的。对感染的恐惧和对并发症的预期导致了抗生素的长期使用。
该研究提供了对手术抗生素预防使用及其实施挑战的理解。部分原因是缺乏本地数据和指南来加强实践。为了改善这一点,需要制定指南,将本地耐药监测数据和增强的抗生素管理计划纳入其中。应该认真考虑如何克服外科医生对并发症的恐惧,因为这会极大地影响当前手术抗生素预防使用的实践。