Caccamo A, Garlaschi C, di Natale B, del Guercio M J, Chiumello G
Helv Paediatr Acta. 1975 Oct;30(3):241-5.
The effect of alpha1-24-corticotropin-Zn on the results of pituitary stimulation tests (moderate standardized physical exercise, arginine infusion, insulin-induced hypoglycemia) was studied in 27 prepubertal children with non-endocrine retardation of growth and development. After administration of 1 mg alpha1-24-corticotropin, the basal blood glucose and plasma cortisol levels rose significantly. However, the growth hormone increase after the three stimulation tests was significantly lower than without the corticotropin injection. The results demonstrate the inhibiting effect of alpha1-24-corticotropin on growth hormone secretion.
在27名患有非内分泌性生长发育迟缓的青春期前儿童中，研究了α1-24-促肾上腺皮质激素锌对垂体刺激试验（适度标准化体育锻炼、精氨酸输注、胰岛素诱发低血糖）结果的影响。给予1毫克α1-24-促肾上腺皮质激素后，基础血糖和血浆皮质醇水平显著升高。然而，三次刺激试验后生长激素的增加显著低于未注射促肾上腺皮质激素的情况。结果表明α1-24-促肾上腺皮质激素对生长激素分泌有抑制作用。
