Shegokar Vijay R, Powar Rajaram M, Joshi Prashant P, Bhargava Aradhana, Dani Vibhawari S, Katti Ravindra, Zare Vasant R, Khanande Vithhalrao D, Jannin Jean, Truc Philippe
Department of Microbiology, Government Medical College, Nagpur, India.
Am J Trop Med Hyg. 2006 Nov;75(5):869-70.
After discovery of the first recorded case of human infection with Trypanosoma evansi, serologic screening of 1,806 persons from the village of origin of the patient in India was performed using the card agglutination test for trypanosomiasis and T. evansi. A total of 410 (22.7%) people were positive by whole blood, but only 81 were confirmed positive by serum. However, no trypanosomes were detected in the blood of 60 people who were positive at a high serum dilution. The results probably indicate frequent exposure of the human population to T. evansi in the study area, which suggests frequent vector transmission of parasites to humans. Although T. evansi is not infective for humans, a follow-up of seropositive persons is required to observe the evolution of human infection with this parasite.
在发现首例有记录的人类感染伊氏锥虫病例后,使用锥虫病和伊氏锥虫的卡片凝集试验,对印度该患者原籍村庄的1806人进行了血清学筛查。共有410人(22.7%)全血检测呈阳性,但血清检测确诊阳性的仅有81人。然而,在血清高稀释度下呈阳性的60人的血液中未检测到锥虫。结果可能表明研究区域的人群经常接触伊氏锥虫,这提示寄生虫经常通过媒介传播给人类。虽然伊氏锥虫对人类无感染性,但仍需对血清阳性者进行随访,以观察人类感染这种寄生虫后的病情发展。