Borras L, de Timary P, Constant E-L, Huguelet P, Eytan A
Pharmacopsychiatry. 2006 Nov;39(6):232. doi: 10.1055/s-2006-951385.
Trazodone, a second generation antidepressant, is helpful in the treatment of lasting alcohol withdrawal symptoms, such as sleep disturbances and craving. We report a case suggesting that trazodone is also efficient for the treatment of the acute phase of alcohol withdrawal treatment. A 30-year-old male patient with severe alcohol withdrawal symptoms was successfully treated with an adjuvant administration of 600 mg trazodone per day, while he had remained symptomatic for several days under high doses of diazepam and clomethiazolum. Controlled trials with trazodone for this indication could be useful.
曲唑酮是一种第二代抗抑郁药，有助于治疗持续的酒精戒断症状，如睡眠障碍和渴望。我们报告了一例病例，提示曲唑酮对酒精戒断治疗急性期也有效。一名30岁男性患者出现严重酒精戒断症状，在高剂量地西泮和氯美噻唑治疗数天仍有症状的情况下，每天辅助使用600毫克曲唑酮成功治愈。针对该适应症进行曲唑酮对照试验可能会有帮助。
