Liew F Y, Cox F E
Dept of Experimental Immunobiology, Wellcome Research Laboratories, Langley Court, Beckenham, UK.
Immunol Today. 1991 Mar;12(3):A17-21. doi: 10.1016/S0167-5699(05)80006-4.
There is a marked contrast between the extraordinary complexity and specificity of the adaptive immune response and the limited number of effector mechanisms that it can direct. Recently, a great deal of interest has focused on the possible role of nitric oxide (NO) in one of these mechanisms. Here F.Y. Liew and Frank Cox examine the evidence supporting a role for NO in parasitic disease and suggest possible mechanism of NO-mediated parasite damage.
适应性免疫反应具有非凡的复杂性和特异性，但其能够指挥的效应机制数量有限，二者之间存在显著差异。最近，大量的研究兴趣集中在一氧化氮（NO）在其中一种机制中可能发挥的作用上。在此，F.Y. 利夫和弗兰克·考克斯研究了支持NO在寄生虫病中发挥作用的证据，并提出了NO介导寄生虫损伤的可能机制。
