Mansour K, Blanksma L J, Vrakking H, Jager P L
Department of Ophthalmology, University Medical Centre Groningen, Groningen, The Netherlands.
Eye (Lond). 2008 Mar;22(3):414-9. doi: 10.1038/sj.eye.6702656. Epub 2006 Nov 24.
To measure the degree of physiological patency of the tear drainage system using dacryoscintigraphy before and after external dacryocystorhinostomy (EDCR) in relation to patient complaints.
Prospective evaluation of 29 eyes of 24 patients with primary acquired nasolacrimal duct obstruction (PANDO) who underwent EDCR. The epiphora complaints were measured subjectively. Dacryoscintigraphy was performed in all eyes preoperatively, and was repeated 6 months after DCR together with the complaints score. For evaluation of dacryoscintigraphy, we determined T1 (percentage of administered dose still present after 1 min) and linear clearance rate (LCR), defined as: 100%(T1-T15)/T1) from the tracer disappearance curve. Dacryoscintigraphy findings were compared with the results of 20 eyes of normal volunteers without any symptoms. Scintigraphic findings were compared before and after the operation, with the change in patient complaints score as well as with normal values.
Significant improvement occurred after the operation in the complaints score, T1 and LCR. However, despite absence of complaints (score=0) postoperative scintigraphic values were still abnormal as compared to normal individuals.
Despite almost complete remission of epiphora complaints, DCR does not result in normalization of the tear drainage system.
通过泪道闪烁造影术测量外路泪囊鼻腔吻合术(EDCR)前后泪道系统的生理通畅程度,并与患者的主诉相关联。
对24例原发性后天性鼻泪管阻塞(PANDO)患者的29只眼睛进行前瞻性评估,这些患者均接受了EDCR。主观测量溢泪主诉。所有眼睛术前均进行泪道闪烁造影术,并在泪囊鼻腔吻合术6个月后重复进行,同时记录主诉评分。为评估泪道闪烁造影术,我们测定了T1(给药后1分钟仍存在的给药剂量百分比)和线性清除率(LCR),其定义为:从示踪剂消失曲线得出的100%(T1 - T15)/T1)。将泪道闪烁造影术的结果与20名无任何症状的正常志愿者的眼睛结果进行比较。比较手术前后的闪烁造影结果、患者主诉评分的变化以及正常值。
术后主诉评分、T1和LCR均有显著改善。然而,尽管术后无主诉(评分 = 0),但与正常个体相比,闪烁造影术的值仍异常。
尽管溢泪主诉几乎完全缓解,但泪囊鼻腔吻合术并未使泪道系统恢复正常。