Pryor Brent, Khaneja Navin
Division of Engineering and Applied Science, Harvard University, Cambridge, Massachusetts 02138, USA.
J Chem Phys. 2006 Nov 21;125(19):194111. doi: 10.1063/1.2390715.
In this paper, we introduce algorithms based on Fourier synthesis for designing phase compensating rf pulse sequences for high-resolution nuclear magnetic resonance (NMR) spectroscopy in an inhomogeneous B0 field. We show that using radio frequency pulses and time varying linear gradients in three dimensions, it is possible to impart the transverse magnetization of spins phase, which is a desired function of the spatial (x,y,z) location. Such a sequence can be used to precompensate the phase that will be acquired by spins at different spatial locations due to inhomogeneous magnetic fields. With this precompensation, the chemical shift information of the spins can be reliably extracted and high resolution NMR spectrum can be obtained.
在本文中，我们介绍了基于傅里叶合成的算法，用于设计在非均匀B0场中进行高分辨率核磁共振（NMR）光谱分析的相位补偿射频脉冲序列。我们表明，通过在三维空间中使用射频脉冲和随时间变化的线性梯度，可以赋予自旋横向磁化强度一个相位，该相位是空间（x,y,z）位置的期望函数。这样的序列可用于预补偿由于磁场不均匀而在不同空间位置的自旋所获得的相位。通过这种预补偿，可以可靠地提取自旋的化学位移信息并获得高分辨率的NMR谱。
