Buyse Sophie, Vibert Eric, Sebagh Mylène, Antonini Teresa, Ichai Philippe, Castaing Denis, Samuel Didier, Duclos-Vallée Jean-Charles
Department of Hepatology and Hepatobiliar Surgery, Centre Hépato-Biliaire and INSERM U785, Hôpital Paul Brousse, 12 avenue Paul Vaillant Couturier, 94800, Villejuif, France.
Liver Transpl. 2006 Dec;12(12):1880-2. doi: 10.1002/lt.20985.
Drug-induced hepatotoxicity is an important cause of hepatocellular injury. Non-nucleoside retroviral transcriptase inhibitors are known to cause hepatotoxicity. We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.
药物性肝毒性是肝细胞损伤的重要原因。已知非核苷类逆转录病毒转录酶抑制剂可导致肝毒性。我们描述了一例由奈韦拉平(维乐命)引起的暴发性肝炎并接受肝移植治疗的详细病例。