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针对与奈韦拉平治疗相关的暴发性肝炎进行肝移植。

Liver transplantation for fulminant hepatitis related to nevirapine therapy.

作者信息

Buyse Sophie, Vibert Eric, Sebagh Mylène, Antonini Teresa, Ichai Philippe, Castaing Denis, Samuel Didier, Duclos-Vallée Jean-Charles

机构信息

Department of Hepatology and Hepatobiliar Surgery, Centre Hépato-Biliaire and INSERM U785, Hôpital Paul Brousse, 12 avenue Paul Vaillant Couturier, 94800, Villejuif, France.

出版信息

Liver Transpl. 2006 Dec;12(12):1880-2. doi: 10.1002/lt.20985.

DOI:10.1002/lt.20985
PMID:17133571
Abstract

Drug-induced hepatotoxicity is an important cause of hepatocellular injury. Non-nucleoside retroviral transcriptase inhibitors are known to cause hepatotoxicity. We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.

摘要

药物性肝毒性是肝细胞损伤的重要原因。已知非核苷类逆转录病毒转录酶抑制剂可导致肝毒性。我们描述了一例由奈韦拉平(维乐命)引起的暴发性肝炎并接受肝移植治疗的详细病例。

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Liver transplantation for fulminant hepatitis related to nevirapine therapy.针对与奈韦拉平治疗相关的暴发性肝炎进行肝移植。
Liver Transpl. 2006 Dec;12(12):1880-2. doi: 10.1002/lt.20985.
2
Nevirapine-induced fulminant hepatitis.
J Assoc Physicians India. 2006 Dec;54:957-8.
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Urgent liver transplantation for nevirapine-induced acute liver failure: report of a case and review of the literature.奈韦拉平所致急性肝衰竭的紧急肝移植:1例报告及文献复习
Ann Transplant. 2012 Jan-Mar;17(1):122-7. doi: 10.12659/aot.882645.
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Severe hepatic failure related to nevirapine treatment.与奈韦拉平治疗相关的严重肝衰竭。
Clin Infect Dis. 1999 Aug;29(2):455-6. doi: 10.1086/520242.
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Adverse effects associated with use of nevirapine in HIV postexposure prophylaxis for 2 health care workers.两名医护人员在使用奈韦拉平进行HIV暴露后预防时出现的不良反应。
JAMA. 2000 Dec 6;284(21):2723.
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Am J Transplant. 2010 Jul;10(7):1713-6. doi: 10.1111/j.1600-6143.2010.03153.x.
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[Reliable effectiveness for years with good long-term tolerance: 10 years nevirapine--a summary].
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Nevirapine-induced Stevens-Johnson syndrome in a pediatric patient.奈韦拉平诱发一名儿科患者出现史蒂文斯-约翰逊综合征。
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Hepatotoxicity and Liver-Related Mortality in Women of Childbearing Potential Living With Human Immunodeficiency Virus and High CD4 Cell Counts Initiating Efavirenz-Containing Regimens.开始含依非韦伦方案的有生育潜力且CD4细胞计数高的感染人类免疫缺陷病毒女性的肝毒性及肝脏相关死亡率
Clin Infect Dis. 2021 Apr 26;72(8):1342-1349. doi: 10.1093/cid/ciaa244.
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Twelfth-Position Deuteration of Nevirapine Reduces 12-Hydroxy-Nevirapine Formation and Nevirapine-Induced Hepatocyte Death.奈韦拉平第十二位氘代减少 12-羟基奈韦拉平的形成和奈韦拉平诱导的肝细胞死亡。
J Med Chem. 2020 Jun 25;63(12):6561-6574. doi: 10.1021/acs.jmedchem.9b01990. Epub 2020 Feb 27.
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Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries.
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Drug Metab Dispos. 2010 Jan;38(1):122-32. doi: 10.1124/dmd.109.028688.
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Practical guidelines for diagnosis and early management of drug-induced liver injury.药物性肝损伤诊断与早期管理实用指南
World J Gastroenterol. 2008 Nov 28;14(44):6774-85. doi: 10.3748/wjg.14.6774.