喉颗粒细胞瘤

Laryngeal granular cell tumor.

作者信息

Arevalo Carlos, Maly Bella, Eliashar Ron, Gross Menachem

机构信息

Department of Otolaryngology/Head & Neck Surgery and Pathology, Hadassah Hebrew-University Hospital, Jerusalem, Israel.

出版信息

J Voice. 2008 May;22(3):339-42. doi: 10.1016/j.jvoice.2006.10.003. Epub 2006 Nov 28.

DOI:10.1016/j.jvoice.2006.10.003

PMID:17134875

Abstract

Granular cell tumor (GCT) of the larynx is an uncommon, benign laryngeal neoplasm. Abrikossoff first described the tumor in 1926 as myoblastoma. The origin of this tumor has been debated in the literature. Most of the authors believe that the tumor is of neural origin due to the characteristic immunohistochemical-staining pattern. The authors describe two cases of laryngeal GCTs located in different sites with a review of the histological and clinical features, the differential diagnosis, and the treatment and the prognosis of the tumor.

摘要

喉颗粒细胞瘤（GCT）是一种罕见的喉部良性肿瘤。1926年，阿布里科索夫首次将该肿瘤描述为成肌细胞瘤。该肿瘤的起源在文献中一直存在争议。大多数作者认为，由于其特征性的免疫组织化学染色模式，该肿瘤起源于神经。作者描述了两例位于不同部位的喉GCT病例，并对肿瘤的组织学和临床特征、鉴别诊断、治疗及预后进行了综述。