声带颗粒细胞瘤：病例报告及文献综述
Granular cell tumor of the vocal cord: Case Report and Literature Review.
作者信息
Cura Melisa B, Labedz Geraldine, Degli Uomini Luciana, Palacios Huatuco René M
机构信息
Department of Otorhinolaryngology, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Oncativo 1248. Córdoba Capital, Argentina.
Department of General Surgery, Clínica Universitaria Reina Fabiola, Universidad Católica de Córdoba, Oncativo 1248. Córdoba Capital, Argentina.
出版信息
Int J Surg Case Rep. 2022 Jun;95:107193. doi: 10.1016/j.ijscr.2022.107193. Epub 2022 May 11.
INTRODUCTION AND IMPORTANCE
Granular cell tumors (GCT) are rare neoplasms. The most common places are the head and neck. The larynx accounts for 3-10% of cases.
PRESENTATION OF CASE
We present the case of a man who consulted our Department of Otorhinolaryngology due to long-term progressive dysphonia without dyspnea or dysphagia. Fibrolaryngoscopy revealed a tumor that affected the left vocal cord. The tumor was surgically resected. The histopathological report revealed a laryngeal GCT. Fourteen months after surgery, the patient had no recurrence.
CLINICAL DISCUSSION
Patients with GCT of the larynx typically have persistent hoarseness, stridor, dysphagia and otalgia, but can also be asymptomatic. A definitive diagnosis is provided by histopathology with immunohistochemistry, and the treatment of choice is surgical resection. Unlike the literature, our report concerns a young man.
CONCLUSION
Granular cell tumor is a rare tumor of the larynx and should be considered a differential diagnosis in all adult men with long-standing dysphonia.
引言与重要性
颗粒细胞瘤（GCT）是一种罕见的肿瘤。最常见的发病部位是头颈部。喉部病例占3%-10%。
病例介绍
我们报告一例男性患者，因长期进行性声音嘶哑前来我院耳鼻喉科就诊，无呼吸困难或吞咽困难。纤维喉镜检查发现肿瘤累及左侧声带。肿瘤经手术切除。组织病理学报告显示为喉部颗粒细胞瘤。术后14个月，患者无复发。
临床讨论
喉部颗粒细胞瘤患者通常表现为持续性声音嘶哑、喘鸣、吞咽困难和耳痛，但也可能无症状。通过组织病理学和免疫组织化学可明确诊断，治疗的首选方法是手术切除。与文献不同的是，我们的报告涉及一名年轻男性。
结论
颗粒细胞瘤是一种罕见的喉部肿瘤，对于所有长期声音嘶哑的成年男性都应考虑将其作为鉴别诊断。
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