酶触发的聚乙二醇连接的寡肽自组装成有序的纳米纤维。
Enzymatically triggered self-assembly of poly(ethylene glycol)-attached oligopeptides into well-organized nanofibers.
作者信息
Koga Tomoyuki, Kitamura Ken-ichi, Higashi Nobuyuki
机构信息
Department of Molecular Science & Technology, Faculty of Engineering, Doshisha University, Kyotanabe, Kyoto, 610-0321, Japan.
出版信息
Chem Commun (Camb). 2006 Dec 21(47):4897-9. doi: 10.1039/b611679e. Epub 2006 Oct 25.
DOI:10.1039/b611679e
PMID:17136239
Abstract
A unique and programmable peptide self-assembling system has been fabricated by using poly(ethylene glycol)-attached amphiphilic oligopeptide, which shows rapid self-assembly into well-organized beta-sheet nanofibers in response to an enzymatic reaction.
摘要
通过使用连接聚乙二醇的两亲性寡肽构建了一种独特且可编程的肽自组装系统，该系统在酶促反应作用下能迅速自组装成有序的β-折叠纳米纤维。
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