Tang H-Y, Zhang Z-G
School of Basic Medicine, Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China.
Amino Acids. 2007 Nov;33(4):689-93. doi: 10.1007/s00726-006-0463-2. Epub 2006 Nov 30.
In this investigation, we attempted to study the backbone geometry of amino acids in peptides using C' deviation. Diameters of distribution were used to describe the various atomic structures, and scatter graphs provided visual evaluation. The length of peptide fragments and the secondary structure of amino acids in the central position of the peptide fragments were also analyzed. The results showed that the atomic distribution of the central amino acids of five-residue peptide fragments was much more restricted than that of their corresponding three-residue peptide fragments. In identical three-residue fragments, atoms of central amino acids with different secondary structures, were distributed in distinct areas.
在本研究中，我们试图利用C'偏差来研究肽中氨基酸的主链几何结构。分布直径用于描述各种原子结构，散点图提供了直观的评估。还分析了肽片段的长度以及肽片段中心位置氨基酸的二级结构。结果表明，五残基肽片段中心氨基酸的原子分布比其相应的三残基肽片段受到的限制要大得多。在相同的三残基片段中，具有不同二级结构的中心氨基酸的原子分布在不同区域。
