Canfell Karen, Sitas Freddy, Beral Valerie
Cancer Epidemiology Research Unit, The Cancer Council New South Wales, Sydney, NSW, Australia.
Med J Aust. 2006 Nov 6;185(9):482-6. doi: 10.5694/j.1326-5377.2006.tb00661.x.
To compare cervical screening policy, screening uptake, and changes in cervical cancer incidence and mortality between Australia and the United Kingdom.
Analysis of screening registry data and national cancer statistics.
In Australia, organised cervical screening was initiated in 1991 for sexually active women aged 18-69 years, with a recommended 2-yearly interval. In the UK, organised screening began in 1988 for women aged 20-64 years, with a recommended 3-yearly interval in most regions.
Estimated lifetime screening participation rates in 2001 were similar in the two countries, at 88% in Australia and 90% in the UK. For women who were screened and had a negative result, the median time to the next screen was 27 months in Australia and 38 months in the UK. At 39 months, equivalent proportions (74%) had been re-screened in the two countries, and by 60 months the re-screened proportions were 81% in Australia and 94% in the UK. From 1991-1993 to 1998-2000, the incidence of cervical cancer in women aged 20-69 years fell by 33% in Australia and 33% in the UK, and mortality from cervical cancer fell by 36% in both countries.
After the introduction of organised screening, similar reductions in cervical cancer incidence and mortality were achieved in Australia and the UK. Therefore, the 2-yearly screening policy in Australia and the predominantly 3-yearly screening policy in the UK appear to have been of broadly similar effectiveness.
比较澳大利亚和英国的宫颈癌筛查政策、筛查接受率以及宫颈癌发病率和死亡率的变化。
对筛查登记数据和国家癌症统计数据进行分析。
在澳大利亚,1991年开始为18 - 69岁的性活跃女性开展有组织的宫颈癌筛查,推荐筛查间隔为两年一次。在英国,1988年开始为20 - 64岁的女性开展有组织的筛查,大多数地区推荐筛查间隔为三年一次。
2001年估计的终生筛查参与率在两国相似,澳大利亚为88%,英国为90%。对于接受筛查且结果为阴性的女性,澳大利亚下次筛查的中位时间为27个月,英国为38个月。在39个月时,两国重新接受筛查的比例相当(74%),到60个月时,澳大利亚重新接受筛查的比例为81%,英国为94%。从1991 - 1993年到1998 - 2000年,20 - 69岁女性的宫颈癌发病率在澳大利亚下降了33%,在英国下降了33%,两国宫颈癌死亡率均下降了36%。
在引入有组织的筛查后,澳大利亚和英国在宫颈癌发病率和死亡率方面都实现了类似程度的降低。因此,澳大利亚的两年一次筛查政策和英国主要的三年一次筛查政策似乎效果大致相似。