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医院和社区药剂师在药物警戒中的作用。

The role of hospital and community pharmacists in pharmacovigilance.

作者信息

van Grootheest A C, de Jong-van den Berg L T W

机构信息

Netherlands Pharmacovigilance Centre Lareb, Hertogenbosch, The Netherlands.

出版信息

Res Social Adm Pharm. 2005 Mar;1(1):126-33. doi: 10.1016/j.sapharm.2004.12.009.

Abstract

In this paper, we give an overview of the role pharmacists actually have and could have in collecting reports of adverse drug reactions (ADRs) and more widely in pharmacovigilance. In the literature, several ways are mentioned in which the pharmacist, both the community pharmacist and the hospital pharmacist, can contribute to the safe use of drugs. In addition to their responsibilities regarding drug dispensing and compliance, they can have a substantial role in ADR reporting. Especially, hospital pharmacists can play a significant role in ADR reporting because the most serious adverse drug events occur in hospitals, and ADRs account for a substantial proportion of hospital admissions. Community pharmacists, however, can also play an important role in ADR reporting. This is, for example, the case in the Netherlands where community pharmacists contribute substantially, both in numbers and in quality of ADR reports. The contribution of the pharmacist to pharmacovigilance should, however, not be limited to ADR reporting. The various pharmaceutical disciplines could also greatly enhance our understanding of the nature of ADRs. If those involved in pharmaceutical disciplines can rise to this challenge, they will significantly help deepen our insights into ADRs.

摘要

在本文中,我们概述了药剂师在收集药品不良反应(ADR)报告以及更广泛的药物警戒方面实际具备和可能发挥的作用。在文献中,提到了社区药剂师和医院药剂师等药剂师可以促进药物安全使用的几种方式。除了他们在药品调配和患者依从性方面的职责外,他们在药品不良反应报告中可以发挥重要作用。特别是,医院药剂师在药品不良反应报告中可以发挥重要作用,因为最严重的药品不良事件发生在医院,且药品不良反应在医院住院病例中占相当大的比例。然而,社区药剂师在药品不良反应报告中也可以发挥重要作用。例如,在荷兰就是这种情况,社区药剂师在药品不良反应报告的数量和质量方面都做出了重大贡献。然而,药剂师对药物警戒的贡献不应局限于药品不良反应报告。各个药学学科也可以极大地增进我们对药品不良反应本质的理解。如果药学学科相关人员能够应对这一挑战,他们将显著有助于加深我们对药品不良反应的认识。

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