Kimelblatt B J, Young S H, Heywood P M, Mandala A R, Gendelman S, Mehl B
Department of Pharmacy, Mount Sinai Medical Center, New York, NY 10029.
Am J Hosp Pharm. 1988 May;45(5):1086-9.
A program using satellite pharmacists to improve adverse drug reaction (ADR) reporting in an 1100-bed teaching hospital is described. Because relying on physicians to report ADRs had met with little success (only six reports in seven years), the pharmacy department proposed that pharmacists in satellite pharmacies on patient-care units be called upon to identify and report ADRs. To begin this program, an ADR team composed of a physician, pharmacist, and nurse made weekly rounds of the satellite pharmacies to assist pharmacists in identifying potential ADRs. The FDA definition of an ADR was adopted. Also, inservice education programs about ADR reporting were conducted for pharmacists and nurses. Currently, suspected ADRs are reported to the satellite pharmacist, who forwards a completed drug reaction report form to the assistant director for clinical pharmacy services. Reports are discussed quarterly by the ADR subcommittee of the pharmacy and therapeutics committee; the sub-committee members determine whether any follow-up action is needed. In the first three years after implementation of this program, 306 ADRs were reported; 90% of the reports were filed by pharmacists. An ADR reporting system based on reporting by staff pharmacists has been effective in increasing the number of reported reactions and pharmacist involvement in monitoring patients for ADRs.
本文介绍了一项在一家拥有1100张床位的教学医院开展的、利用卫星药房药师改善药品不良反应（ADR）报告的项目。由于依靠医生报告ADR收效甚微（七年仅有六份报告），药房部门提议让患者护理单元卫星药房的药师负责识别和报告ADR。为启动该项目，一个由医生、药师和护士组成的ADR团队每周巡查卫星药房，协助药师识别潜在的ADR。采用了美国食品药品监督管理局（FDA）对ADR的定义。此外，还为药师和护士开展了关于ADR报告的在职教育项目。目前，疑似ADR会报告给卫星药房药师，药师会将填好的药品不良反应报告表转交给临床药学服务助理主任。药学与治疗学委员会的ADR小组委员会每季度对报告进行讨论；小组委员会成员决定是否需要采取后续行动。在该项目实施后的头三年里，共报告了306例ADR；90%的报告由药师提交。基于药房药师报告的ADR报告系统在增加报告的不良反应数量以及药师参与监测患者ADR方面很有效。
