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成年早期内化症状的结构。

Structure of internalising symptoms in early adulthood.

作者信息

Fergusson David M, Horwood L John, Boden Joseph M

机构信息

Christchurch Health and Development Study, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand.

出版信息

Br J Psychiatry. 2006 Dec;189:540-6. doi: 10.1192/bjp.bp.106.022384.

Abstract

BACKGROUND

Debate surrounds the underlying structure of internalising disorders including major depression, generalised anxiety disorder, phobias and panic disorders.

AIMS

To model the within-time and across-time relationships of internalising symptoms, incorporating effects from generalised internalising and disorder-specific components of continuity.

METHOD

Data were gathered from a 25-year longitudinal study of a birth cohort of 953 New Zealand children. Outcome measures included DSM-IV symptom scores for major depression, generalised anxiety disorder, phobia and panic disorder at the ages of 18, 21 and 25 years.

RESULTS

Structural equation modelling showed that, within-times, a common underlying measure of generalised internalising explained symptom score comorbidities. Across-time correlation of symptom scores was primarily accounted for by continuity over time in generalised internalising. However, for major depression and phobia there was also evidence of across-time continuity in the disorder-specific components of symptoms.

CONCLUSIONS

Internalising symptoms can be partitioned into components reflecting both a generalised tendency to internalising and disorder-specific components.

摘要

背景

关于内化性障碍(包括重度抑郁症、广泛性焦虑症、恐惧症和惊恐障碍)的潜在结构存在争议。

目的

建立内化症状的即时和跨时关系模型,纳入广泛性内化和特定障碍连续性成分的影响。

方法

数据来自对953名新西兰儿童出生队列的25年纵向研究。结果测量包括18岁、21岁和25岁时重度抑郁症、广泛性焦虑症、恐惧症和惊恐障碍的DSM-IV症状评分。

结果

结构方程模型显示,在即时情况下,广泛性内化的一个共同潜在测量指标解释了症状评分的共病情况。症状评分的跨时相关性主要由广泛性内化随时间的连续性所解释。然而,对于重度抑郁症和恐惧症,症状的特定障碍成分也存在跨时连续性的证据。

结论

内化症状可分为反映广泛性内化倾向的成分和特定障碍成分。

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