Chitayat D, Kalousek D K, McGillivary B C, Applegarth D A
Department of Pediatrics, Montreal Children's Hospital, McGill University, Quebec, Canada.
Pediatr Pathol. 1991 May-Jun;11(3):487-91. doi: 10.3109/15513819109064784.
An elevated amniotic fluid alpha-fetoprotein (AF-AFP) level together with a positive acetylcholinesterase (AChE) band is strongly predictive of neural tube defect (NTD) in the fetus. We report such results in a pregnancy in which the fetus was found to be normal after termination. Among the placental fragments was found a sac containing a prenatally undetected co-twin fetus papyraceus. We suggest that pregnant women with such laboratory results but lacking sonographic evidence of NTD should have a high-level untrasonographic investigation, as well as a thorough pathologic examination of both placenta and fetus in cases of termination.
羊水甲胎蛋白（AF-AFP）水平升高且乙酰胆碱酯酶（AChE）带呈阳性，强烈提示胎儿神经管缺陷（NTD）。我们报告了这样一例妊娠情况，终止妊娠后发现胎儿正常。在胎盘碎片中发现一个囊，囊内有一个产前未检测到的纸样双胎胎儿。我们建议，对于有此类实验室检查结果但缺乏NTD超声证据的孕妇，应进行高水平超声检查，并且在终止妊娠的情况下，对胎盘和胎儿进行全面的病理检查。
