Khaykin Yaariv
Southlake Regional Health Center, Newmarket, Ontario, Canada.
Curr Opin Cardiol. 2007 Jan;22(1):11-7. doi: 10.1097/HCO.0b013e32801129d7.
Catheter ablation for atrial fibrillation is a rapidly evolving field. It has been adopted at many institutions worldwide. This review compares the efficacy and cost of catheter ablation and medical therapy in atrial fibrillation patients.
There is emerging evidence for clinical superiority of catheter ablation over medical therapy for restoring and maintaining sinus rhythm in atrial fibrillation patients. Early analyses of costs related to catheter ablation in atrial fibrillation suggest that medical therapy and catheter ablation become cost-equivalent at about 5 years of follow-up. A recent cost-effectiveness study concluded that catheter ablation is a cost-effective alternative to medical care in younger and older patients at low and moderate risk of stroke, assuming that restoration and maintenance of sinus rhythm with ablation would have some protective effect with respect to embolic events.
Catheter ablation is a potentially cost-effective strategy in select patients with atrial fibrillation. Long-term randomized studies that compare it to conventional care and focus on outcomes of morbidity and mortality are necessary prior to widespread application of this technique.
心房颤动的导管消融是一个快速发展的领域。它已在全球许多机构得到应用。本综述比较了心房颤动患者导管消融与药物治疗的疗效和成本。
越来越多的证据表明,在恢复和维持心房颤动患者的窦性心律方面,导管消融在临床上优于药物治疗。对心房颤动导管消融相关成本的早期分析表明,在大约5年的随访中,药物治疗和导管消融的成本相当。最近一项成本效益研究得出结论,对于中风风险低和中等的年轻及老年患者,导管消融是一种具有成本效益的医疗替代方案,前提是消融恢复和维持窦性心律对栓塞事件有一定的保护作用。
导管消融对于某些心房颤动患者可能是一种具有成本效益的策略。在广泛应用该技术之前,有必要进行长期随机研究,将其与传统治疗进行比较,并关注发病率和死亡率等结果。