通过液体辅助研磨探索共晶体-共晶体反应性：外消旋共晶体的组装和对映体共晶体的拆解
Exploring cocrystal-cocrystal reactivity via liquid-assisted grinding: the assembling of racemic and dismantling of enantiomeric cocrystals.
作者信息
Friscić Tomislav, Fábián László, Burley Jonathan C, Jones William, Motherwell W D Samuel
机构信息
Pfizer Institute for Pharmaceutical Materials Science, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.
出版信息
Chem Commun (Camb). 2006 Dec 28(48):5009-11. doi: 10.1039/b613073a. Epub 2006 Nov 9.
DOI:10.1039/b613073a
PMID:17146510
Abstract
The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
摘要
通过液体辅助研磨研究了涉及咖啡因或茶碱与手性共晶形成剂的对映体共晶对之间的反应
我们证明了此类共晶 - 共晶反应有两种不同的结果。
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