Iannicelli E, Sessa B, Argnani L, Galluzzo A, David V
U.O.C. di Radiodiagnostica, Ospedale Sant'Andrea, II Facoltà di Medicina e Chirurgia Università degli Studi di Roma La Sapienza, Roma, Italia.
Clin Ter. 2006 Sep-Oct;157(5):425-9.
To evaluate the diagnostic accuracy of MR cholangiopancreatography (MRCP) in biliary tree patology in comparison with percutaneous transhepatic cholangiography (PTC), endoscopic retrograde cholangiopancreatography (ERCP) and surgical findings.
Forty-six patients , with clinical and laboratory findings suggestive of biliary tree pathology, and after an abdominal US, underwent MRCP with a 1.5 T superconductive magnet equipped with a phased-array body coil. MR exam was performed with baseline sequences for the examination of the upper abdomen, followed by specific MRCP sequences and, in cases of suspected neoplastic disease, completed with abdominal sequences after a bolus injection of paramagnetic contrast.
MRCP showed normal findings in 16/46 patients, biliary duct dilatation in 25/46 patients (7 choledocolithiasis, 10 benign obstructions and 8 neoplastic stenoses) and stenoses without dilatation of biliary tree in 5/46 patients. In 25 patients with biliary duct dilatation, CPRM correctly identified the level of in 100% of patients (25/25) and the nature in 88% of patients (22/25). In 5 patients with stenosis without dilatation of biliary tree, CPRM identified 2 true positives (sclerosing cholangitis), 2 false positives and 1 patient is still in follow-up.
In our experience MRCP proved to be highly accurate as fundamental diagnostic step in patients with clinical and laboratory findings suggestive of biliary disease. The workload of ERCP, invasive method with risk of complications, in the diagnosis stage could therefore be reduced and its use be reserved for therapeutic indications.
与经皮经肝胆管造影(PTC)、内镜逆行胰胆管造影(ERCP)及手术结果相比较,评估磁共振胰胆管造影(MRCP)对胆管系统病变的诊断准确性。
46例临床及实验室检查结果提示胆管系统病变的患者,在进行腹部超声检查后,采用配备相控阵体线圈的1.5T超导磁体行MRCP检查。MR检查采用上腹部检查的基线序列,随后进行特定的MRCP序列,对于怀疑有肿瘤性疾病的病例,在静脉注射顺磁性对比剂后完成腹部序列检查。
MRCP检查显示,46例患者中16例结果正常,25例(7例胆总管结石、10例良性梗阻和8例肿瘤性狭窄)胆管扩张,5例胆管无扩张的狭窄。在25例胆管扩张的患者中,CPRM正确识别出100%患者(25/25)的梗阻部位及88%患者(22/25)的病变性质。在5例胆管无扩张的狭窄患者中,CPRM识别出2例假阳性(硬化性胆管炎)、2例假阳性,1例患者仍在随访中。
根据我们的经验,MRCP作为对临床及实验室检查结果提示胆管疾病患者的基本诊断步骤,已证明具有高度准确性。因此,在诊断阶段可以减少有并发症风险的侵入性检查ERCP的工作量,并将其应用保留用于治疗目的。