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接受全胃肠外营养的术后患者的低磷血症:营养支持团队的影响

Hypophosphatemia in postoperative patients with total parenteral nutrition: influence of nutritional support teams.

作者信息

Martínez M J, Martínez M A, Montero M, Campelo E, Castro I, Inaraja M T

机构信息

Pharmacy Department, Meixoeiro Hospital, Vigo, Pontevedra, Spain.

出版信息

Nutr Hosp. 2006 Nov-Dec;21(6):657-60.

Abstract

UNLABELLED

PURPOSE, SETTING AND SUBJECTS: We conducted a prospective, descriptive study of postoperative patients under total parenteral nutrition controlled by a Multidisciplinary Nutritional Support Team in a tertiary care hospital. Between january 2002 and november 2003. Data of nutritional status, nutritional support, hypophosphatemia, electrolyte and metabolic complications were reviewed.

RESULTS

215 postoperative patients (63.3% male, 68 +/- 13.9 years old, 47.4% neoplasia). were included. Nutritional support according nutritional needs was made during fasting 14.2 +/- 18.4 days. Mild-moderate initial malnutrition was present in 58% of patients. 18.1% developed postoperative hypophosphatemia 96 hours after starting total parenteral nutrition containing phosphate. 37.7% patients showed moderated and 6.5% severe hypophosphatemia. Nutritional intervention corrected hypophosphatemia (p < 0.001). Factors related to hypophosphatemia were hypokalemia, hypomagnesemia, hypercalcemia, female sex, neoplasia, 96-hour postoperative period and duration of nutrition.

CONCLUSIONS

Prevalence of hypophosphatemia in postoperative patients with total parenteral nutrition is high and needs timely monitoring. The intervention of Multidisciplinary Nutritional Support Team is effective detecting and correcting postoperative hypophosphatemia.

摘要

未标注

目的、背景与研究对象:我们在一家三级护理医院对由多学科营养支持团队控制进行全胃肠外营养的术后患者开展了一项前瞻性描述性研究。研究时间为2002年1月至2003年11月。对营养状况、营养支持、低磷血症、电解质及代谢并发症的数据进行了回顾。

结果

纳入了215例术后患者(男性占63.3%,年龄68±13.9岁,47.4%为肿瘤患者)。根据营养需求在禁食期间进行营养支持的时间为14.2±18.4天。58%的患者存在轻度至中度初始营养不良。18.1%的患者在开始含磷全胃肠外营养96小时后出现术后低磷血症。37.7%的患者表现为中度低磷血症,6.5%为重度低磷血症。营养干预纠正了低磷血症(p<0.001)。与低磷血症相关的因素有低钾血症、低镁血症、高钙血症、女性、肿瘤、术后96小时以及营养持续时间。

结论

接受全胃肠外营养的术后患者中低磷血症的发生率较高,需要及时监测。多学科营养支持团队的干预在检测和纠正术后低磷血症方面是有效的。

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