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[对新生儿期诊断为巨细胞病毒感染的儿童进行随访、神经学和心理学调查的结果(作者译)]

[Results of catamnestic, neurological and psychological investigations in children suffering from cytomegaly virus infection, diagnosed in neonates (author's transl)].

作者信息

Castell R, Jung F, Käckell M Y, Lenard H G

出版信息

Klin Padiatr. 1975 May;187(3):227-34.

PMID:171471
Abstract

Report on results of follow-up in 10 children, in 9 of whom clinical findings at the age between 6 and 11 months suggested the diagnosis of connatal cytomegaly. All 10 children secreted cytomegaly virus in the urine. In 3 of them post-natal infection appears probable. Follow-up was carried out at the ages between 3 and 5.9 years. Physical development was delayed in 4, severe neurologic damage occurred in 2, medium severe or minimal, in part reversible, neurologic signs in 3 childrens. The 2 most severely neurologically damaged children could not be examined psychologically. The IQ of the other 8 was between 92 and 105. 3 children showed in individual other tests only minor, insignificant loss of performance, 2 more pronounced defects which suggested cerebral damage.

摘要

10名儿童的随访结果报告,其中9名在6至11个月大时的临床症状提示先天性巨细胞病毒感染。所有10名儿童尿液中均分泌巨细胞病毒。其中3名可能为产后感染。随访在3至5.9岁进行。4名儿童身体发育迟缓,2名出现严重神经损伤,3名儿童有中度严重或轻度、部分可逆的神经体征。2名神经损伤最严重的儿童无法进行心理检查。其他8名儿童的智商在92至105之间。3名儿童在个别其他测试中仅表现出轻微、无明显意义的功能丧失,另外2名有更明显的缺陷,提示脑损伤。

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