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香港公立医院采用动脉栓塞术治疗原发性产后出血

Management of primary postpartum haemorrhage with arterial embolisation in Hong Kong public hospitals.

作者信息

Yong S P Y, Cheung K B

机构信息

Department of Obstetrics and Gynaecology, Tuen Mun Hospital, Tuen Mun, Hong Kong.

出版信息

Hong Kong Med J. 2006 Dec;12(6):437-41.

PMID:17148796
Abstract

OBJECTIVE

To assess the utilisation, effectiveness, and safety of arterial (angiographic) embolisation for management of severe primary postpartum haemorrhage in Hong Kong public hospitals. DESIGN. Retrospective study.

SETTING

All eight obstetrics and gynaecology units of the Hospital Authority in Hong Kong.

PATIENTS

Women who underwent arterial embolisation for primary postpartum haemorrhage from July 1999 to June 2004 inclusive.

MAIN OUTCOME MEASURES

Cause of primary postpartum haemorrhage, estimated blood loss, patient condition before embolisation, and the intervals between the diagnosis of postpartum haemorrhage and the procedure.

RESULTS

Primary postpartum haemorrhage occurred in 7200 (3.9%) cases of 183,700 deliveries; 90 (0.05%) underwent total hysterectomy, whilst 29 (0.016%) received angiographic embolisation. Arterial embolisation was 90% effective in treating medically uncontrollable primary postpartum haemorrhage, except in three patients who failed to respond and underwent a hysterectomy. All 29 patients survived, although due to severe haemorrhage one had a cardiac arrest, whilst another had transient right-leg claudication. Six patients developed mild fever.

CONCLUSIONS

In Hong Kong, arterial embolisation for severe primary postpartum haemorrhage is a safe and effective treatment modality but is underutilised. If first-line medical treatment fails and patients are haemodynamically stable, the procedure should be considered an alternative management option. A prompt decision and early resort to arterial embolisation are advisable so as to reduce the morbidity and avoid resorting to open surgery.

摘要

目的

评估香港公立医院采用动脉(血管造影)栓塞术治疗严重原发性产后出血的应用情况、有效性及安全性。设计:回顾性研究。

地点

香港医院管理局的所有8个妇产科单位。

患者

1999年7月至2004年6月期间因原发性产后出血接受动脉栓塞术的女性。

主要观察指标

原发性产后出血的原因、估计失血量、栓塞术前患者状况,以及产后出血诊断与手术之间的间隔时间。

结果

在183,700例分娩中,原发性产后出血发生7200例(3.9%);90例(0.05%)接受了全子宫切除术,而29例(0.016%)接受了血管造影栓塞术。动脉栓塞术治疗药物无法控制的原发性产后出血的有效率为90%,但有3例患者无反应并接受了子宫切除术。所有29例患者均存活,尽管1例因严重出血发生心脏骤停,另1例出现短暂性右腿跛行。6例患者出现低热。

结论

在香港,动脉栓塞术治疗严重原发性产后出血是一种安全有效的治疗方式,但未得到充分利用。如果一线药物治疗失败且患者血流动力学稳定,应考虑将该手术作为替代治疗选择。建议迅速做出决定并尽早采用动脉栓塞术,以降低发病率并避免进行开放手术。

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Pathological findings in a case of failed uterine artery embolization for placenta previa.前置胎盘子宫动脉栓塞失败病例的病理检查结果
Jpn Clin Med. 2013 Apr 14;4:25-8. doi: 10.4137/JCM.S11317. eCollection 2013.
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Obstetric and gynecologic emergencies: a review of indications and interventional techniques.妇产科急症:适应证与介入技术综述
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