Walker Melanie, Kim Hojoong, Samii Ali
Department of Neurology, University of Washington School of Medicine, Seattle, Washington, USA.
Mov Disord. 2007 Jan 15;22(2):272-4. doi: 10.1002/mds.21271.
Holmes tremor is an arrhythmic, 2- to 5-Hz resting, postural, and kinetic upper extremity movement disorder that occurs weeks to months after acute mesencephalic pathology. We present a patient who developed tremor in three body parts postbrainstem hemorrhage with subsequent hypertrophic olivary degeneration and discuss the relevant clinical evolution. Our case is unique because in addition to expected upper extremity and cervical dystonic head tremors, the patient also developed a severe lower extremity movement disorder, which we believe to be a form of Holmes tremor. Tremor involving the lower extremity in this setting has not been previously reported.
霍姆斯震颤是一种节律不齐的上肢运动障碍,静息、姿势和运动时均有,频率为2至5赫兹,发生于急性中脑病变数周或数月之后。我们报告一名患者,其在脑干出血后三个身体部位出现震颤,随后发生肥大性橄榄核变性,并讨论相关的临床演变过程。我们的病例很独特,因为除了预期的上肢和颈部肌张力障碍性头部震颤外,患者还出现了严重的下肢运动障碍,我们认为这是霍姆斯震颤的一种形式。此前尚未有在这种情况下涉及下肢震颤的报道。