Homma Y, Ozawa T, Higashihara E, Aso Y
Department of Urology, University of Tokyo.
Nihon Hinyokika Gakkai Zasshi. 1991 May;82(5):792-8. doi: 10.5980/jpnjurol1989.82.792.
Prostate thermotherapy consisting of 6 sessions of intrarectal 60 min irradiation of 915 MHz microwave generated by a prostathermer (Blodan, Isreal) was performed once or twice a week on 30 patients with benign prostatic hyperplasia. Excluding 2 cases who refused further therapy at the first session because of rectal discomfort, 28 cases were evaluated for the efficacy of the treatment. Good or fair improvement in subjective symptoms was observed in 24 (85.7%) of the cases. Nocturia was significantly relieved from 2.9 to 2.0 a night. Among the objective responses, no improvement was achieved as to residual urine or prostate size, while a significant increase of maximum or average flow rate on uroflowmetry was observed. Adverse effects were minor or moderate, including 2 cases of urethral bleeding and rectal discomfort, 2 cases of lower urinary tract infection and 1 case of hypotension, which occurred at the 5th session. The scoring criteria taking into account of both subjective and objective responses showed that the efficacy is good in 10 cases (33.3%) and fair or good in 20 cases (66.7%). These results indicated the usefulness of the prostathermer as one of non-surgical therapies for benign prostatic hyperplasia.
对30例良性前列腺增生患者进行前列腺热疗,使用前列腺热疗仪(以色列Blodan公司)经直肠进行6次照射,每次60分钟,频率为915兆赫,每周进行1次或2次。排除2例因直肠不适在首次治疗时拒绝进一步治疗的患者,对28例患者的治疗效果进行评估。24例(85.7%)患者主观症状有良好或中等改善。夜尿次数从每晚2.9次显著减少至2.0次。在客观反应方面,残余尿量和前列腺大小无改善,但尿流率测定显示最大或平均尿流率显著增加。不良反应轻微或中等,包括2例尿道出血和直肠不适、2例下尿路感染以及1例在第5次治疗时出现的低血压。综合主观和客观反应的评分标准显示,10例(33.3%)患者疗效良好,20例(66.7%)患者疗效中等或良好。这些结果表明前列腺热疗仪作为良性前列腺增生的非手术治疗方法之一是有用的。