Honda N, Uchida T, Mukai N, Go M, Yokoyama E, Mashimo S, Endo T, Ishibashi A, Koshiba K, Shibuya M
Department of Urology, Kitasato University School of Medicine.
Nihon Hinyokika Gakkai Zasshi. 1991 May;82(5):830-3. doi: 10.5980/jpnjurol1989.82.830.
We report a case of an extragonadal germ cell tumor in the retrovesical region. The patient complained of a perineal and micturition pain. Urethrography, CT and MRI showed a retrovesical tumor protruding into the bladder. Alfa-fetoprotein was increased to 12,170 ng/ml. Bilateral testes did not contain any palpable mass by careful palpation. No tumor was detected by ultrasonography, either. Clinically, he was diagnosed as having a retrovesical extragonadal germ cell tumor associated with paraaortic lymph-nodes and bilateral pulmonary metastases. Although he was treated by combination chemotherapy (PVB and VAB-6 regimen) and irradiation, he died of carcinomatosis about 6 months after the admission. There was no evidence of tumor in bilateral testes on autopsy. This case was a second case of extragonadal germ cell tumor originating from the retrovesical lesion in the literature.
我们报告一例膀胱后区域的性腺外生殖细胞肿瘤。患者主诉会阴部疼痛及排尿疼痛。尿道造影、CT和MRI显示膀胱后有一肿瘤突入膀胱。甲胎蛋白升高至12,170 ng/ml。仔细触诊双侧睾丸未触及任何肿块。超声检查也未发现肿瘤。临床上，他被诊断为膀胱后性腺外生殖细胞肿瘤伴腹主动脉旁淋巴结及双侧肺转移。尽管接受了联合化疗（PVB和VAB - 6方案）及放疗，但入院后约6个月死于癌转移。尸检时双侧睾丸未发现肿瘤证据。该病例是文献中第二例起源于膀胱后病变的性腺外生殖细胞肿瘤。
