Three-dimensional structure of the ternary complex of yeast tyrosyl-tRNA synthetase. - Suppr | 超能文献

Three-dimensional structure of the ternary complex of yeast tyrosyl-tRNA synthetase.

作者信息

Tsunoda Masaru, Kusakabe Yoshio, Tanaka Nobutada, Ohno Satoshi, Nakamura Masashi, Senda Toshiya, Sekine Mitsuo, Yokogawa Takashi, Nishikawa Kazuya, Nakamura Kazuo T

机构信息

School of Pharmaceutical Sciences, Showa University, Tokyo 142-8555, Japan.

出版信息

Nucleic Acids Symp Ser (Oxf). 2004(48):155-6. doi: 10.1093/nass/48.1.155.

DOI:10.1093/nass/48.1.155

Abstract

The archaeal/eukaryotic tyrosyl tRNA synthetase (TyrRS)-tRNA(Tyr) pairs do not cross-react with their prokaryotic counterparts. Recently, crystal structure analyses of prokaryotic and archaeal TyrRSs complexed with their cognate tRNA(Tyr) have been reported, however, no structure is available for eukaryotic TyrRS complexed with its cognate tRNA(Tyr). Here we report the crystal structure of yeast Tyrosyl-tRNA synthetase (yTyrRS) complexed with its cognate tRNA(Tyr) and Tyr-AMP analog.

摘要

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