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社区样本中强迫症与精神障碍的终生共病情况。

Lifetime comorbidity of obsessive-compulsive disorder with psychiatric disorders in a community sample.

作者信息

Mohammadi Mohammad-Reza, Ghanizadeh Ahmad, Moini Rozita

机构信息

Department of Psychiatry, Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Depress Anxiety. 2007;24(8):602-7. doi: 10.1002/da.20259.

Abstract

Epidemiological research indicates that obsessive-compulsive disorder (OCD) still constitutes a major public health problem. To study the comorbidity of psychiatric disorders in OCD subjects in a non-Western community sample, 25,180 individuals were interviewed face-to-face at home according to DSM-IV for diagnosis of psychiatric disorders by 250 trained clinical psychologists. The subjects were predetermined with a randomized cluster sampling method among all families residing in Iran. From 444 individuals diagnosed as OCD, 157 (35.4%) developed at least one of the psychiatric disorders. The most common comorbid psychiatric disorders were major depressive disorder and simple phobia. Comorbidity of two or more additional psychiatric disorders in OCD individuals was rare. There was no difference between genders in the comorbidity of psychiatric disorders with OCD. Low comorbidity of psychiatric disorders with OCD shows that OCD tends to occur in isolated rather than as cluster problems in a clinical sample.

摘要

流行病学研究表明,强迫症(OCD)仍然是一个重大的公共卫生问题。为了在非西方社区样本中研究强迫症患者的精神障碍共病情况,250名经过培训的临床心理学家按照《精神疾病诊断与统计手册》第四版(DSM-IV),对25180名个体进行了上门面对面访谈,以诊断精神障碍。这些受试者是在居住在伊朗的所有家庭中采用随机整群抽样方法预先确定的。在444名被诊断为强迫症的个体中,157名(35.4%)出现了至少一种精神障碍。最常见的共病精神障碍是重度抑郁症和单纯恐惧症。强迫症患者合并两种或更多其他精神障碍的情况很少见。在精神障碍与强迫症的共病方面,性别之间没有差异。精神障碍与强迫症的低共病率表明,在临床样本中,强迫症倾向于单独出现,而不是以集群问题的形式出现。

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