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基于切伦科夫辐射的电子射野成像:一种新方法及其可行性

Electronic portal imaging based on cerenkov radiation: a new approach and its feasibility.

作者信息

Mei X, Rowlands J A, Pang G

机构信息

Toronto-Sunnybrook Regional Cancer Centre, 2075 Bayview Avenue, Toronto M4N 3M5, Canada.

出版信息

Med Phys. 2006 Nov;33(11):4258-70. doi: 10.1118/1.2362875.

DOI:10.1118/1.2362875
PMID:17153404
Abstract

Most electronic portal imaging devices (EPIDs) developed so far use a Cu plate/phosphor screen to absorb x rays and convert their energies into light, and the light image is then read out. The main problem with this approach is that the Cu plate/phosphor screen must be thin (approximately 2 mm thick) in order to obtain a high spatial resolution, resulting in a low x-ray absorption or low quantum efficiency for megavoltage x rays (typically 2-4%). In addition, the phosphor screen contains high atomic number (high-Z) materials, resulting in an over-response of the detector to low-energy x rays in dosimetric verification. In this paper, we propose a new approach that uses Cerenkov radiation to convert x-ray energy absorbed by the detector into light for portal imaging applications. With our approach, a thick (approximately 10-30 cm) energy conversion layer made of a low-Z dielectric medium, such as a large-area, thick fiber-optic taper consisting of a matrix of optical fibers aligned with the incident x rays, is used to replace the thin Cu plate/phosphor screen. The feasibility of this approach has been investigated using a single optical fiber embedded in a solid material. The spatial resolution expressed by the modulation transfer function (MTF) and the sensitivity of the detector at low doses (approximately one Linac pulse) have been measured. It is predicted that, using this approach, a detective quantum efficiency of an order of magnitude higher at zero frequency can be obtained while maintaining a reasonable MTF, as compared to current EPIDs.

摘要

目前开发的大多数电子射野影像装置(EPID)都使用铜板/磷光屏来吸收X射线并将其能量转换为光,然后读出光图像。这种方法的主要问题在于,为了获得高空间分辨率,铜板/磷光屏必须很薄(约2毫米厚),这导致对兆伏级X射线的X射线吸收低或量子效率低(通常为2 - 4%)。此外,磷光屏包含高原子序数(高Z)材料,导致探测器在剂量验证中对低能X射线过度响应。在本文中,我们提出了一种新方法,即利用切伦科夫辐射将探测器吸收的X射线能量转换为光用于射野成像应用。采用我们的方法,用由低Z介电介质制成的厚(约10 - 30厘米)能量转换层,例如由与入射X射线对齐的光纤矩阵构成的大面积厚光纤锥,来替代薄铜板/磷光屏。已使用嵌入固体材料中的单根光纤研究了这种方法的可行性。测量了由调制传递函数(MTF)表示的空间分辨率以及探测器在低剂量(约一个直线加速器脉冲)下的灵敏度。据预测,与当前的EPID相比,采用这种方法在保持合理MTF的同时,在零频率下可获得高一个数量级的探测量子效率。

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