Zhu Jingzhi, Kurihara Yasuyuki, Kanemaki Yoshihide, Ogata Haruki, Fukuda Mamoru, Nakajima Yasuo, Maeda Ichiro
Department of Radiology, St. Marianna University School of Medicine, Sugao, Kawasaki City Kanagawa, Japan.
J Magn Reson Imaging. 2007 Jan;25(1):96-103. doi: 10.1002/jmri.20809.
To prospectively evaluate the accuracy of high-resolution (HR)-MRI as a secondary examination in women with abnormal calcifications detected on mammography.
We used a 4.7-cm microscopy coil to acquire HR-MRI signal data. We examined 52 women with breast lesions preoperatively using HR-MRI and vacuum-assisted core needle biopsy. The lesions were suspicious of malignancy, classified as category 3-5 on mammography (Breast Imaging Reporting and Data System [BI-RADS]), and without a palpable mass. All visualized suspicious lesions were correlated with histological findings. We compared the HR-MRI and pathological findings and calculated the sensitivity, specificity, and accuracy.
We compared the breast HR-MRI results with the gold standard of pathological results for studies of malignancy (DCIS and invasive cancer), and found a sensitivity of 88.5%, specificity of 92.3%, and accuracy of 90.4%. The positive predictive value (PPV) was 92%, and the negative predictive value (NPV) was 88.9%. When breast MRI was compared with pathological results for studies that diagnosed DCIS only, the results revealed a sensitivity of 88.6%, specificity of 88.2%, accuracy of 88.5%, PPV of 93.9%, and NPV of 78.9%.
HR-MRI using a microscopy coil is a useful, reliable, safe, and minimally invasive procedure that is a good choice for secondary assessment of abnormal calcification in the breast.
前瞻性评估高分辨率（HR）-MRI作为乳腺钼靶检查发现异常钙化女性的二次检查手段的准确性。
我们使用4.7厘米的显微线圈采集HR-MRI信号数据。术前我们对52例乳腺病变女性进行了HR-MRI和真空辅助芯针活检检查。这些病变怀疑为恶性，在乳腺钼靶检查（乳腺影像报告和数据系统[BI-RADS]）中分类为3-5类，且无可触及肿块。所有可视化的可疑病变均与组织学结果相关。我们比较了HR-MRI和病理结果，并计算了敏感性、特异性和准确性。
我们将乳腺HR-MRI结果与恶性肿瘤（导管原位癌和浸润性癌）研究的病理结果金标准进行比较，发现敏感性为88.5%，特异性为92.3%，准确性为90.4%。阳性预测值（PPV）为92%，阴性预测值（NPV）为88.9%。当仅将乳腺MRI与诊断导管原位癌的研究的病理结果进行比较时，结果显示敏感性为88.6%，特异性为88.2%，准确性为88.5%，PPV为93.9%，NPV为78.9%。
使用显微线圈的HR-MRI是一种有用、可靠、安全且微创的检查方法，是乳腺异常钙化二次评估的良好选择。
