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[不同节段交感神经切除术治疗手掌多汗症的疗效比较]

[Comparison of curative effects of sympathectomy at different segments on palmar hyperhidrosis].

作者信息

Lin Min, Tu Yuan-rong, Li Xu, Lai Fan-cai, Chen Jian-feng, Dai Zu-jian

机构信息

Department of Thoracic Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2006 Sep 5;86(33):2315-7.

Abstract

OBJECTIVE

To compare the curative effects of sympathectomy at different segments on palmar hyperhidrosis.

METHODS

Four hundred patients with palmar hyperhidrosis, 191 males and 209 females, aged 21.9 +/- 3.4 (10 - 53), underwent bilateral sympathectomy However, bilateral sympathectomy was forced to be given up and replaced by unilateral sympathectomy in 2 patients because of severe pleural adhesion The 398 patients on which bilateral sympathectomy was successfully performed were randomly divided into 3 groups: Group A (n = 207) undergoing T2-4 sympathectomy, Group B (n = 131) undergoing T3 sympathectomy, and Group C (n = 60) undergoing T3-4 sympathectomy. The curative effects were compared.

RESULTS

Operation was successfully performed on all patients and their palmar hyperhidrosis was completely alleviated after operation. No surgery-related post-operative complication occurred. The compensatory hyperhidrosis (CH) rate of Group B was 5.3%, not significantly different from that of Group C (6.7%, P > 0.05). The CH rate of the combined group, Group B + C was 5.8%, significantly lower than that of Group A (28.0%, P < 0.01).

CONCLUSION

Safe and mini-invasive, T3 or T3-4 sympathectomy effectively reduce the development of CH and improves the patients' quality of life post-operatively.

摘要

目的

比较不同节段交感神经切除术治疗手掌多汗症的疗效。

方法

400例手掌多汗症患者,男191例,女209例,年龄21.9±3.4(10 - 53)岁,均接受双侧交感神经切除术。然而,2例患者因严重胸膜粘连被迫放弃双侧交感神经切除术,改为单侧交感神经切除术。成功实施双侧交感神经切除术的398例患者随机分为3组:A组(n = 207)行T2 - 4交感神经切除术,B组(n = 131)行T3交感神经切除术,C组(n = 60)行T3 - 4交感神经切除术。比较疗效。

结果

所有患者手术均成功,术后手掌多汗症完全缓解。未发生与手术相关的术后并发症。B组代偿性多汗症(CH)发生率为5.3%,与C组(6.7%)差异无统计学意义(P > 0.05)。B组和C组合并组的CH发生率为5.8%,显著低于A组(28.0%,P < 0.01)。

结论

T3或T3 - 4交感神经切除术安全、微创,能有效降低CH的发生率,提高患者术后生活质量。

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