[HIV 患者的细菌性脑膜炎：考虑合并感染！]

[Bacterial meningitis in HIV patient: think about co-infections!].

作者信息

Nadaud J, Villevieille T, Boulland P, Allanic L, Plancade D, Steiner T, Favier J-C, Rüttimann M, Puyhardy J-M

机构信息

Département d'anesthésie-réanimation-urgences, hôpital d'instruction des Armées-Legouest, avenue de Plantières, BP 10, 57998 Metz-Armées, France.

出版信息

Ann Fr Anesth Reanim. 2007 Jan;26(1):85-7. doi: 10.1016/j.annfar.2006.06.024. Epub 2006 Dec 8.

DOI:10.1016/j.annfar.2006.06.024

PMID:17158018

Abstract

The authors report the case of an African 34-year-old patient who was admitted to the intensive care unit for bacterial meningitis due to Streptococcus pneumoniae. A meningeal co-infection due to Cryptococcal neoformans was found the 3rd day in an HIV infection context. Cryptococcus neoformans detection in cerebrospinal fluid, using the India-ink stain, has a low sensibility which imposes the search of cryptococcal antigen and the culture of cerebrospinal fluid. These last two exams have a sensibility of at least 90%.

摘要

作者报告了一例34岁非洲患者的病例，该患者因肺炎链球菌引起的细菌性脑膜炎入住重症监护病房。在人类免疫缺陷病毒（HIV）感染背景下，于第3天发现了新型隐球菌引起的脑膜合并感染。使用墨汁负染法在脑脊液中检测新型隐球菌，敏感性较低，因此需要检测隐球菌抗原并进行脑脊液培养。后两项检查的敏感性至少为90%。