抗癫痫药物的精神otropic作用。 （注：原文中“Psychotropic”可能拼写有误，推测正确拼写为“Psychotropic”，意为“精神otropic的”，常见释义为“影响精神的” 。整体译文为“抗癫痫药物的精神影响作用” ，但按照要求未添加解释说明 。）
Psychotropic effects of antiepileptic drugs.
作者信息
Ettinger Alan B
机构信息
EEG Lab, North Shore-LIJ, Comprehensive Epilepsy Centers, 270-05 76th Ave., New Hyde Park, NY 11040, USA.
出版信息
Neurology. 2006 Dec 12;67(11):1916-25. doi: 10.1212/01.wnl.0000247045.85646.c0.
BACKGROUND
Mood disorder symptoms are common in patients with epilepsy. Since antiepileptic drugs (AEDs) can affect these symptoms, knowledge of the psychotropic properties of AEDs is crucial. We review most studies of the psychotropic effects of AEDs that have involved potential psychiatric applications and have been reported in the psychiatric literature.
METHODS
We conducted a comprehensive literature search to identify relevant clinical trial reports on the efficacy of AEDs for mood disorders.
RESULTS
There have been few randomized controlled trials studying AED psychotropic properties in patients with epilepsy, but some randomized controlled trials of potential psychiatric indications for AEDs have been published. Data from these studies suggest that specific AEDs have mood stabilizing, anxiolytic, and antidepressant properties, while others may elicit depression, agitation, or psychosis.
CONCLUSION
Antiepileptic drug selection should consider potential effects on mood and behavior.
背景
情绪障碍症状在癫痫患者中很常见。由于抗癫痫药物（AEDs）会影响这些症状，了解AEDs的精神药理学特性至关重要。我们回顾了大多数涉及潜在精神科应用且已在精神科文献中报道的AEDs精神药理学效应的研究。
方法
我们进行了全面的文献检索，以确定关于AEDs治疗情绪障碍疗效的相关临床试验报告。
结果
很少有随机对照试验研究癫痫患者中AEDs的精神药理学特性，但已发表了一些关于AEDs潜在精神科适应证的随机对照试验。这些研究的数据表明，特定的AEDs具有情绪稳定、抗焦虑和抗抑郁特性，而其他一些药物可能引发抑郁、激越或精神病。
结论
抗癫痫药物的选择应考虑对情绪和行为的潜在影响。
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