Papavasiliou Kyriakos A, Kirkos John M, Kapetanos George A, Pournaras John
3rd Orthopaedic Department, Aristotle University of Thessaloniki-Medical School, Papageorgiou General Hospital, Thessaloniki, Greece.
J Pediatr Orthop B. 2007 Jan;16(1):1-5. doi: 10.1097/BPB.0b013e328010b73d.
The potential influence of hormonal imbalance on the development of slipped capital femoral epiphysis was assessed through a prospective clinical study. The serum levels of T3, T4, thyroid-stimulating hormone, testosterone, estradiol, dehydroepiandrosterone-sulfate, follicle-stimulating hormone, luteinizing hormone, human growth hormone, adrenal cortex hormone and cortisol were evaluated in seven boys and seven girls. Forty-three out of 154 hormonal determinations (27.9%) were abnormal. The results showed increased incidence of pathological values mainly in the levels of follicle-stimulating-hormone, luteinizing-hormone and testosterone. No patient had clinical findings of endocrinopathy. A (possibly) temporary hormonal disorder may play a potentially significant role in the development of slipped capital femoral epiphysis.
通过一项前瞻性临床研究评估了激素失衡对股骨头骨骺滑脱发展的潜在影响。对7名男孩和7名女孩的血清T3、T4、促甲状腺激素、睾酮、雌二醇、硫酸脱氢表雄酮、促卵泡激素、黄体生成素、人生长激素、肾上腺皮质激素和皮质醇水平进行了评估。154项激素测定中有43项(27.9%)异常。结果显示,主要在促卵泡激素、黄体生成素和睾酮水平上,病理值的发生率增加。没有患者有内分泌病的临床发现。一种(可能)暂时的激素紊乱可能在股骨头骨骺滑脱的发展中起潜在的重要作用。