du Bois A, Rasenack R, Dziekan G, Siebers J W, Hillemanns H G
UFK Freiburg, St.-Josefs-Krankenhaus Offenburg.
Geburtshilfe Frauenheilkd. 1991 Jun;51(6):443-9. doi: 10.1055/s-2007-1026175.
Fetomaternal bleeding in pregnancy is the most common cause of rhesus immunization. In this study we evaluated the amount of fetomaternal bleeding during pregnancies with and without complications. The data from 1204 patients are analyzed. Fetomaternal bleeding was of clinical relevance (HbF greater than 0.01%) in 6% of all uncomplicated pregnancies. There was no increased fetomaternal bleeding in pregnancies complicated by gestosis, preliminary labour, placenta praevia, trauma, and diabetes in pregnancy. In cases with premature rupture of the amnion or vaginal bleeding in pregnancy we observed an increased percentage of fetomaternal bleeding into the mother's circulation. Nearly 25% of all patients with hydrops fetalis had clinical relevant fetomaternal bleeding (HbF greater than 0.01%).
孕期母胎输血是恒河猴免疫的最常见原因。在本研究中,我们评估了有无并发症的孕期母胎输血量。分析了1204例患者的数据。在所有无并发症的妊娠中,6%的母胎输血具有临床相关性(胎儿血红蛋白大于0.01%)。妊娠期高血压疾病、早产、前置胎盘、创伤和妊娠期糖尿病等并发症并不会增加母胎输血量。在胎膜早破或孕期阴道出血的病例中,我们观察到母胎输血进入母亲循环的比例增加。几乎25%的胎儿水肿患者有临床相关的母胎输血(胎儿血红蛋白大于0.01%)。