腺苷脱氨酶（ADA）和腺苷酸脱氨酶（AMPDA）催化2',3'-O-异丙叉腺苷-5'-羧酸的脱氨作用：底物电离对酶活性的影响。
Deamination of 2',3'-O-isopropylideneadenosine-5'- carboxylic acid catalyzed by adenosine deaminase (ADA) and adenylate deaminase (AMPDA): influence of substrate ionization on the activity of the enzymes.
作者信息
Ciuffreda Pierangela, Alessandrini Laura, Pavlovic Radmila, Santaniello Enzo
机构信息
Dipartimento di Scienze Precliniche LITA Vialba, Università degli Studi di Milano, Milano, Italy.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2007;26(1):121-7. doi: 10.1080/15257770601052356.
PMID:17162592
Abstract
Adenosine deaminase (ADA) and adenylate deaminase (AMPDA) catalyze the deamination of 2 ',3 '-O-isopropylideneadenosine-5'-carboxylic acid to the corresponding inosine derivative and dependence of the rate of enzymatic reaction on the ionization degree of the substrate has been studied at different pH values.
摘要
腺苷脱氨酶（ADA）和腺苷酸脱氨酶（AMPDA）催化2'，3'-O-异丙叉腺苷-5'-羧酸脱氨生成相应的肌苷衍生物，并在不同pH值下研究了酶促反应速率对底物电离度的依赖性。
Zotero 插件