腺苷脱氨酶和腺苷酸脱氨酶对腺苷及2',3(')-异亚丙基腺苷的活性：不同pH值下保护基团的作用
Activity of adenosine deaminase and adenylate deaminase on adenosine and 2', 3(')-isopropylidene adenosine: role of the protecting group at different pH values.
作者信息
Alessandrini Laura, Ciuffreda Pierangela, Pavlovic Radmila, Santaniello Enzo
机构信息
Dipartimento di Scienze Precliniche LITA Vialba, Università degli Studi di Milano, Milano, Italy.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2008 Jan;27(1):31-6. doi: 10.1080/15257770701571776.
PMID:18188767
Abstract
The deamination rate of 2',3'-isopropylidene adenosine catalyzed by adenosine deaminase (ADA) from calf intestine and adenylate deaminase (AMPDA) from Aspergillus species has been evaluated and compared with that of the enzymatic reactions of adenosine, to elucidate the influence of the protecting group on enzyme activity.
摘要
已对来自小牛肠的腺苷脱氨酶（ADA）和来自曲霉菌种的腺苷酸脱氨酶（AMPDA）催化的2'，3'-异丙叉腺苷的脱氨速率进行了评估，并与腺苷的酶促反应速率进行了比较，以阐明保护基团对酶活性的影响。
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