Vieira Tiago O, Green Mike J, Alper Howard
Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada K1N 6N5.
Org Lett. 2006 Dec 21;8(26):6143-5. doi: 10.1021/ol062646n.
[Structure: see text] A general, highly efficient and regioselective methoxycarbonylation, by means of a palladium-salicylicborate-catalyzed protocol, of terminal alkyl and aryl olefins is described. The substrates include aliphatic alkenes, allylbenzenes, and styrene derivatives. The yields are very good (60-92%) and the regioselectivity, in favor of the linear ester, is up to quantitative--unprecedented in the case of styrenes.
[结构：见正文] 本文描述了一种通过钯-水杨酸硼酸酯催化的方法，对末端烷基和芳基烯烃进行的通用、高效且区域选择性的甲氧羰基化反应。底物包括脂肪族烯烃、烯丙基苯和苯乙烯衍生物。产率非常高（60 - 92%），并且区域选择性倾向于线性酯，高达定量——在苯乙烯的情况下是前所未有的。
