Resh Brooke, Jones Evan, Glaser Dee Anna
UCSD School of Medicine, La Jolla, CA, USA.
J Cosmet Dermatol. 2005 Jun;4(2):78-82. doi: 10.1111/j.1473-2165.2005.40205.x.
Urticaria pigmentosa is a cutaneous disorder involving infiltration of the skin with mast cells. Histologically the papillary dermis has an increased number of mast cells with an increase in basal layer pigmentation. In addition to possible systemic symptoms, patients with urticaria pigmentosa can suffer emotionally from the cosmetic nature of this skin disease.
The purpose was to investigate the use of a diode-pumped Nd:YAG laser at 532 nm for the treatment of the cosmetic comorbidity of urticaria pigmentosa lesions.
A 19-year-old white male with urticaria pigmentosa had multiple lesions on the dorsum of the hands and forearms. A test site on the right inner arm was treated with a DioLite 532 nanometer laser. Because of satisfaction with the treatment of the test site lesions, multiple lesions on the dorsal hands and forearms were also treated with the DioLite 532 nanometer laser.
There was a dramatic clinical reduction in the amount of lesions on the dorsum of the hands and forearms. The test site lesions on the right inner arm had not recurred.
The diode-pumped Nd:YAG laser at 532 nanometers should be considered part of a dermatologist's armamentarium for the treatment of a patient's cosmetic concerns with lesions of cutaneous mastocytosis.
色素性荨麻疹是一种皮肤疾病，涉及肥大细胞浸润皮肤。组织学上，乳头层真皮中肥大细胞数量增加，基底层色素沉着增多。除了可能出现的全身症状外，色素性荨麻疹患者还会因这种皮肤病的外观问题而在情绪上受到影响。
研究使用532nm二极管泵浦Nd:YAG激光治疗色素性荨麻疹皮损的外观合并症。
一名19岁患有色素性荨麻疹的白人男性，其双手背部和前臂有多处皮损。右侧上臂内侧的一个试验部位用DioLite 532纳米激光进行治疗。由于对试验部位皮损的治疗效果满意，双手背部和前臂的多处皮损也用DioLite 532纳米激光进行了治疗。
双手背部和前臂的皮损数量在临床上显著减少。右侧上臂内侧试验部位的皮损未复发。
532纳米二极管泵浦Nd:YAG激光应被视为皮肤科医生治疗皮肤肥大细胞增多症患者外观问题的武器库的一部分。
