与FKBP结合的FK-506类似物[U-13C]子囊霉素的核磁共振研究：子囊霉素参与结合的构象和区域 - Suppr

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超能文献

NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding.

作者信息

Petros A M, Gampe R T, Gemmecker G, Neri P, Holzman T F, Edalji R, Hochlowski J, Jackson M, McAlpine J, Luly J R

机构信息

Pharmaceutical Discovery Division, Abbott Laboratories, Abbott Park, Illinois 60064.

出版信息

J Med Chem. 1991 Sep;34(9):2925-8. doi: 10.1021/jm00113a037.

DOI:10.1021/jm00113a037

PMID:1716684

Abstract

摘要

相似文献

NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding.与FKBP结合的FK-506类似物[U-13C]子囊霉素的核磁共振研究：子囊霉素参与结合的构象和区域

J Med Chem. 1991 Sep;34(9):2925-8. doi: 10.1021/jm00113a037.

NMR studies of an FK-506 analog, [U-13C]ascomycin, bound to FK-506-binding protein.

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1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin.与子囊霉素结合时FK506结合蛋白的1H、13C和15N归属及二级结构

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FEBS Lett. 1992 Aug 24;308(3):309-14. doi: 10.1016/0014-5793(92)81300-b.

Heteronuclear 3D NMR studies of water bound to an FK506 binding protein/immunosuppressant complex.

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Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR.通过异核三维和四维核磁共振确定溶液中FK506结合蛋白/子囊霉素复合物的三维结构。

Biochemistry. 1993 Jan 26;32(3):754-65. doi: 10.1021/bi00054a004.

Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants.根据3JHα、Hβ和3HN、Hβ偶合常数确定FKBP与子囊霉素结合时的立体特异性归属和chi 1旋转异构体。

FEBS Lett. 1992 Jun 29;305(2):137-43. doi: 10.1016/0014-5793(92)80881-g.

Solution structure of FK506 bound to FKBP-12.与FKBP-12结合的FK506的溶液结构

FEBS Lett. 1992 May 4;302(1):89-96. doi: 10.1016/0014-5793(92)80292-o.

Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.

Science. 1991 May 10;252(5007):839-42. doi: 10.1126/science.1709302.

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