Seleznev S A, Goriunov A V, Shiliaev R R
Biofizika. 1991 May-Jun;36(3):419-23.
It was demonstrated that human and horse hemoglobin variants having quantitative difference in the interaction with dipalmitoyllecithin exhibit features of generality. The latter is manifested in the established hydrophobic contacts between protein and lipid in hydrated films discovered by IR spectroscopy. The arrangement of hydrophobicity profiles of hemoproteins demonstrated in amino acid sequences of chains the existence of intermittent hydrophobic and hydrophilic regions. Such a composition of hemoglobins could underlie their property to participate in hydrophobic interactions with lipids.
结果表明，在与二棕榈酰卵磷脂的相互作用上存在定量差异的人和马血红蛋白变体具有普遍性特征。后者表现为通过红外光谱在水合膜中发现的蛋白质与脂质之间已确定的疏水接触。血红蛋白疏水轮廓的排列在链的氨基酸序列中表明存在间歇性的疏水和亲水区域。这种血红蛋白的组成可能是其参与与脂质疏水相互作用特性的基础。
